Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3273189 | 0.81 | MAOA (0.37) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| SCHEMBL23272971 | 0.75 | ACHE (0.41) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL28990011 | 0.74 | MAOA (0.32) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| SCHEMBL29174120 | 0.73 | ACHE (0.39) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| SCHEMBL28302269 | 0.73 | ACHE (0.40) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL28219420 | 0.72 | HTR7 (0.37) | ACHECYP1A2CYP2A6ELANECHRNB2 | |
| Hydrochloric Acid SCHEMBL28994366 | 0.70 | ACHE (0.32) | ACHECYP1A2CYP2A6CHRNB2CHRNA4 | |
| SCHEMBL28502522 | 0.70 | ACHE (0.37) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| SCHEMBL27637676 | 0.70 | ACHE (0.36) | ACHEMAOAMAOBCYP1A2CYP2A6 | |
| Toluene SCHEMBL27459088 | 0.68 | LMNA (0.48) | ACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567961-B | Ethylene/alpha-olefin random copolymer for photovoltaic adhesive film and application thereof | 万华化学集团股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-108137729-B | Catalysts for forming multimodal polymers | 埃克森美孚化学专利公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-108137729-A | It is used to form the catalyst of multimodal polymer | 埃克森美孚化学专利公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-1632505-B1 | ETHYLENE POLYMER | MITSUI CHEMICALS INC (JP) | 2016-09-07 | — | — | EP | disclosed |
| CN-100595202-C | Crosslinked metallocene compound for olefin polymerization and olefin polymerization method using the same | MITSUI CHEMICALS INC | 2010-03-24 | — | — | CN | disclosed |
| US-7452946-B2 | copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst | MITSUI CHEMICALS, INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-20060199925-A1 | Ethylene polymer | MITSUI CHEMICALS, INC. (JP) | 2006-09-07 | — | — | US | disclosed |
| CN-1791619-A | Ethylene polymer | MITSUI CHEMICALS INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| EP-1632505-A1 | ETHYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2006-03-08 | — | — | EP | disclosed |
| CN-1684968-A | Crosslinked metallocene compound for olefin polymerization and olefin polymerization method using the same | MITSUI CHEMICALS INC (JP) | 2005-10-19 | — | — | CN | disclosed |