Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926780 | 0.89 | LMNA (0.48) | LMNAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL9542638 | 0.83 | KDM4E (0.48) | LMNAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL9542646 | 0.83 | KDM4E (0.48) | LMNAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL27854166 | 0.79 | PTPN1 (0.55) | LMNAMAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27681024 | 0.79 | PTPN1 (0.55) | LMNAMAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4840569 | 0.77 | MMP8 (0.45) | POLBMAPTALDH1A1 | |
| SCHEMBL4837953 | 0.76 | MAPT (0.53) | LMNAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL4838439 | 0.75 | MMP8 (0.44) | MAPTALDH1A1 | |
| SCHEMBL4838046 | 0.74 | MMP8 (0.42) | LMNAPOLBALDH1A1 | |
| SCHEMBL30681423 | 0.74 | PTPN1 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | LMNA 1943/4885POLB 4775/4885MAPT 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.