Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GNRHR | P30968 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 10/20 | 0.43 |
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644486 | 0.83 | ALDH1A1 (0.52) | TDP1PKMMMP2MAPTMAPK1 | |
| SCHEMBL4833652 | 0.81 | MAPT (0.43) | TDP1PKMGNRHRMMP2MMP8 | |
| SCHEMBL4836363 | 0.77 | MMP2 (0.41) | TDP1MMP2MAPTMAPK1LMNA | |
| SCHEMBL4842119 | 0.77 | MMP2 (0.41) | PKMMMP2MAPTMAPK1LMNA | |
| SCHEMBL3593098 | 0.75 | RORC (0.41) | TDP1MMP2LMNAKMT2A | |
| SCHEMBL926563 | 0.75 | NPSR1 (0.48) | TDP1MMP2MMP8MMP3MAPT | |
| SCHEMBL2519672 | 0.74 | ESR1 (0.56) | TDP1MMP2MMP8MMP3MAPT | |
| SCHEMBL2519677 | 0.74 | ESR1 (0.56) | TDP1MMP2MMP8MMP3MAPT | |
| SCHEMBL2519247 | 0.72 | ALDH1A1 (0.53) | MMP2MMP8MMP3MAPK1KMT2A | |
| SCHEMBL2519245 | 0.72 | ALDH1A1 (0.53) | MMP2MMP8MMP3MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | TDP1 779/4885PKM 1415/4885GNRHR 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.