Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833128 | 0.94 | TRPA1 (0.39) | TRPA1RORC | |
| SCHEMBL4839534 | 0.93 | TRPA1 (0.42) | TRPA1RARARARBRARGRORC | |
| SCHEMBL4838303 | 0.93 | TRPA1 (0.38) | TRPA1PPARDRARARARBRARG | |
| SCHEMBL4843418 | 0.93 | TRPA1 (0.36) | TRPA1PPARDRORCPPARGPPARA | |
| SCHEMBL4842895 | 0.92 | TRPA1 (0.39) | TRPA1PPARDRARARARBRARG | |
| SCHEMBL4841408 | 0.92 | TRPA1 (0.36) | TRPA1PPARDRORCPPARGPPARA | |
| SCHEMBL4841126 | 0.92 | RORC (0.40) | TRPA1RARARARBRARGRORC | |
| SCHEMBL4845030 | 0.88 | ALDH1A1 (0.40) | TRPA1RORC | |
| SCHEMBL4842782 | 0.88 | TRPA1 (0.39) | TRPA1RORC | |
| SCHEMBL4838028 | 0.88 | TRPA1 (0.42) | TRPA1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | TRPA1 368/4885PPARD 258/4885RARA 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.