Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838190 | 0.95 | LTA4H (0.53) | LTA4HKEAP1NFE2L2LOXL2PDE3B | |
| Hydrochloric Acid SCHEMBL25376075 | 0.94 | LTA4H (0.52) | LTA4HKEAP1NFE2L2LOXL2PDE3B | |
| SCHEMBL24675523 | 0.93 | LTA4H (0.47) | LTA4HKEAP1NFE2L2PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL25250800 | 0.92 | LTA4H (0.46) | LTA4HKEAP1NFE2L2PDE3BPDE3A | |
| SCHEMBL1668551 | 0.90 | LTA4H (0.52) | LTA4HKEAP1NFE2L2LOXL2ALDH1A1 | |
| SCHEMBL4275826 | 0.87 | HDAC1 (0.56) | LTA4HPDE3BPDE3AP2RY12HDAC8 | |
| SCHEMBL765954 | 0.86 | LMNA (0.55) | LTA4HALDH1A1LMNAMAPTHTT | |
| SCHEMBL4832834 | 0.85 | LOXL2 (0.49) | LTA4HLOXL2PDE3BPDE3AP2RY12 | |
| SCHEMBL4275916 | 0.84 | LTA4H (0.52) | LTA4HPDE3BPDE3AP2RY12HDAC8 | |
| SCHEMBL13104320 | 0.84 | LMNA (0.53) | LTA4HPDE3BPDE3AP2RY12HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746214-A | Novel indoline compounds | FOURNIER LAB SA | 2012-10-24 | — | — | CN | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
| EP-0712405-A1 | DERIVATIVES OF MONIC ACIDS A AND C HAVING ANTIBACTERIAL, ANTIMYCOPLASMATICAL, ANTIFUNGAL AND HERBICIDAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995005384-A1 | DERIVATIVES OF MONIC ACIDS A AND C HAVING ANTIBACTERIAL, ANTIMYCOPLASMATICAL, ANTIFUNGAL AND HERBICIDAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | LTA4H 1742/4885KEAP1 236/4885NFE2L2 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.