Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844392 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4839053 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4839063 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4843171 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4843158 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4842654 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4842647 | 0.97 | ALDH1A1 (0.45) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4838794 | 0.95 | MTNR1B (0.47) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4838804 | 0.95 | MTNR1B (0.47) | ALDH1A1HPGDMTNR1BMTNR1AKMT2A | |
| SCHEMBL4839994 | 0.93 | LMNA (0.46) | ALDH1A1HPGDKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378428-B2 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222138-A1 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | PARK7, MMP8, CDK7 | ALDH1A1 2636/4885HPGD 1185/4885MTNR1B 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.