Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100124 | 0.94 | DHFR (0.41) | DHFRPOLBHTTIKBKB | |
| SCHEMBL48459 | 0.89 | HTT (0.50) | DHFRPOLBHTTBACE1 | |
| SCHEMBL3937871 | 0.88 | POLB (0.40) | DHFRPOLBHTTBACE1 | |
| SCHEMBL3945176 | 0.88 | POLB (0.40) | DHFRPOLBHTTBACE1 | |
| SCHEMBL5377222 | 0.86 | SKP2 (0.39) | DHFRHTT | |
| SCHEMBL11497456 | 0.85 | HTT (0.47) | DHFRPOLBHTTBACE1 | |
| SCHEMBL11413476 | 0.84 | SHBG (0.40) | DHFRPOLBIKBKB | |
| SCHEMBL31614612 | 0.82 | DHFR (0.35) | DHFRPOLBHTT | |
| SCHEMBL6131303 | 0.82 | GABRA1 (0.37) | DHFRPOLBHTT | |
| SCHEMBL8861189 | 0.82 | SHBG (0.41) | DHFRHTTIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| US-7084194-B2 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-08-01 | — | — | US | disclosed |
| US-6900269-B2 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-05-31 | — | — | US | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| US-20040158023-A1 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-08-12 | — | — | US | disclosed |
| US-20040147640-A1 | Halogen-free resin composition | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-07-29 | — | — | US | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| US-5686557-A | Polyamide resin which can be dissolved in alcohol solvent, composition thereof, and method of use thereof | TOMOEGAWA PAPER CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | DHFR 1624/4885POLB 1238/4885HTT 2124/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | DHFR 1297/4885POLB 1310/4885HTT 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.