SCHEMBL4845956

SCHEMBL4845956

CCC(C)O[P@@](=O)(O)C(CC(=O)c1ccc(Cl)cc1)NC(=O)OCC(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.42
▸ HTT P42858 2/20 0.38
▸ POLB P06746 3/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ LMNA P02545 3/20 0.35
▸ TSHR P16473 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ TRPA1 O75762 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4856863 0.92 L3MBTL1 (0.39) L3MBTL1HTTPOLBSMN1; SMN2MAPT
SCHEMBL4855199 0.91 ALDH1A1 (0.35) L3MBTL1HTTALDH1A1MAPTLMNA
SCHEMBL4853494 0.91 L3MBTL1 (0.32) L3MBTL1HTTSMN1; SMN2LMNA
SCHEMBL5712076 0.91 KMT2A (0.38) SMN1; SMN2ALDH1A1
SCHEMBL4852580 0.90 KMT2A (0.38) L3MBTL1HTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL4853708 0.89 SLC6A4 (0.39) ALDH1A1MAPTHPGD
SCHEMBL4856627 0.82 MEN1 (0.30) —
SCHEMBL4857423 0.82 KMO (0.41) L3MBTL1HTTSMN1; SMN2ALDH1A1MAPT
SCHEMBL4845948 0.81 MAPT (0.43) L3MBTL1HTTPOLBSMN1; SMN2ALDH1A1
SCHEMBL4845951 0.81 MAPT (0.43) L3MBTL1HTTPOLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1724275-B1 PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE JAPAN SCIENCE & TECH AGENCY (JP) 2015-04-08 — — EP disclosed
US-7375244-B2 Production method for aminophosphonic acid derivatives JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-05-20 — — US disclosed
US-20070142658-A1 Production method for aminophosphonic acid derivatives JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-06-21 — — US disclosed
EP-1724275-A1 PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE Japan Science and Technology Agency (JP) 2006-11-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142658-A1 Production method for aminophosphonic acid derivatives AASDHPPT, NPEPPS, DAO L3MBTL1 2832/4885HTT 4618/4885POLB 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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