SCHEMBL4847238

SCHEMBL4847238

Cl[Si](Cl)(Cl)c1ccc(CBr)cc1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131361 0.76 ALDH1A1 (0.67) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL937352 0.76 CA1 (0.39)
SCHEMBL5552238 0.74 ESR1 (0.31)
SCHEMBL121642 0.74 TRPA1 (0.43) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL3481645 0.74 TP53 (0.43) ALDH1A1TSHR
SCHEMBL4841453 0.74
SCHEMBL1395217 0.70 LPL (0.45) ALDH1A1
SCHEMBL15398568 0.70 TRPA1 (0.59) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL1579879 0.70 TRPA1 (0.40) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL1766 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101196462-B Bionic molecular recognition nano sensing film of optical fibre sensor and method for producing the same FIRST INST OCEANOGRAPHY SOA 2011-06-08 CN disclosed
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
CN-101196462-A Bionic molecular recognition nano sensing film of optical fibre sensor and method for producing the same FIRST INST OCEANOGRAPHY SOA (CN) 2008-06-11 CN disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed
US-4478963-A CRACK RESISTANT COATINGS THE B. F. GOODRICH COMPANY (US) 1984-10-23 US disclosed