Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163642 | 0.82 | GSK3A (0.35) | CASP3ALDH1A1 | |
| SCHEMBL802733 | 0.78 | ALDH1A1 (0.40) | CASP3ALDH1A1 | |
| SCHEMBL23974872 | 0.76 | — | — | |
| SCHEMBL15281062 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1420111 | 0.68 | RAD51 (0.48) | ALDH1A1TP53ALOX15HSD17B10 | |
| SCHEMBL6850987 | 0.67 | GSK3A (0.44) | CASP3ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL19543253 | 0.67 | F2 (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL13878863 | 0.67 | DUSP3 (0.35) | CASP3ALDH1A1TP53CYP2C19HSD17B10 | |
| SCHEMBL19721765 | 0.67 | MEN1 (0.31) | CASP3 | |
| SCHEMBL19059392 | 0.67 | BCL2A1 (0.32) | CASP3ALDH1A1TP53HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117276665-A | Electrolyte of high-nickel ternary lithium ion battery, and preparation method and application thereof | 湖南法恩莱特新能源科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-20150191488-A1 | METHODS FOR THE ACYLATION OF MAYTANSINOL | IMMUNOGEN, INC. | 2015-07-09 | — | — | US | disclosed |
| US-7378419-B2 | 9-amino-podophyllotoxin derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | LES LABORATOIRES SERVIER (FR) | 2008-05-27 | — | — | US | disclosed |
| EP-1664055-B9 | 9-AMINO-PODOPHYLLOTOXIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SERVIER LAB (FR) | 2007-10-10 | — | — | EP | disclosed |
| EP-1664055-B1 | 9-AMINO-PODOPHYLLOTOXIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SERVIER LAB (FR) | 2006-12-13 | — | — | EP | disclosed |
| US-20060247246-A1 | 9-Amino-podophyllotoxin derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191488-A1 | METHODS FOR THE ACYLATION OF MAYTANSINOL | NAAA, NPPA, AANAT | CASP3 2729/4885ALDH1A1 1322/4885TP53 4274/4885 |
| US-20060247246-A1 | 9-Amino-podophyllotoxin derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives | SIK2, PTK2B, PLK2 | CASP3 1062/4885ALDH1A1 3950/4885TP53 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.