Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403300 | 0.87 | MAOA (0.56) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL4847777 | 0.87 | HPRT1 (0.50) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL21703801 | 0.85 | PNMT (0.41) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL29520144 | 0.83 | DNMT1 (0.44) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL867598 | 0.83 | DNMT1 (0.44) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL4848717 | 0.83 | MAOA (0.43) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL13562191 | 0.80 | ACHE (0.44) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL13562177 | 0.80 | NPC1 (0.37) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL815143 | 0.80 | MAOA (0.34) | MAOANPC1RAB9AKDM4EMAPT | |
| SCHEMBL13562173 | 0.80 | TDP1 (0.40) | MAOANPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876182-B2 | Thieno-containing compounds and processes and uses thereof | UNIVERSITY OF OREGON (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | UNIVERSITY OF OREGON (US) | 2016-06-09 | — | — | US | disclosed |
| US-7470290-B2 | Hydroscopic polymer gels for easier cleaning | THE CLOROX COMPANY (US) | 2008-12-30 | — | — | US | disclosed |
| US-7183010-B2 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-20050245428-A1 | Hydroscopic polymer gels for easier cleaning | RODRIGUES KLIN A | 2005-11-03 | — | — | US | disclosed |
| US-20040076853-A1 | Organic light-emitting diode devices with improved operational stability | EASTMAN KODAK COMPANY | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | TERT, TES, DDT | MAOA 375/4885NPC1 4803/4885RAB9A 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.