Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207376 | 0.84 | G6PD (0.55) | G6PDCASP7CASP6KMT2AALOX15 | |
| SCHEMBL28229430 | 0.84 | ALDH1A1 (0.54) | CYP3A4CYP2C9KMT2AALOX15ALDH1A1 | |
| SCHEMBL4865222 | 0.84 | UCHL1 (0.50) | G6PDCASP7CASP6KMT2AALDH1A1 | |
| SCHEMBL1148444 | 0.82 | ALDH1A1 (0.50) | ALOX15ALDH1A1LMNAPOLBCA2 | |
| SCHEMBL4849042 | 0.81 | MMP2 (0.45) | G6PDCASP7CASP6CYP3A4CYP2C9 | |
| SCHEMBL4251057 | 0.81 | MYC (0.47) | G6PDCASP7CASP6KMT2AALOX15 | |
| SCHEMBL30663932 | 0.80 | ALDH1A1 (0.48) | CYP3A4CYP2C9KMT2AALOX15ALDH1A1 | |
| SCHEMBL39249 | 0.80 | ALDH1A1 (0.56) | ALOX15ALDH1A1CDC25BLMNATAS2R14 | |
| SCHEMBL31028133 | 0.80 | ALDH1A1 (0.56) | ALOX15ALDH1A1CDC25BLMNATAS2R14 | |
| SCHEMBL4737094 | 0.79 | ALDH1A1 (0.54) | ALOX15ALDH1A1CDC25BLMNATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342039-B2 | Substituted indole oximes | WYETH (US) | 2008-03-11 | — | — | US | disclosed |
| US-20050119326-A1 | Substituted aryloximes | WYETH (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119326-A1 | Substituted aryloximes | IDO2, TDO2, IDO1 | G6PD 1104/4885CASP7 2514/4885CASP6 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.