SCHEMBL4849353

SCHEMBL4849353

Cc1cccc(C)c1O[Bi](Oc1c(C)cccc1C)Oc1c(C)cccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
CYP2A6 P11509 1/20 0.41
SCN4A P35499 9/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 2/20 0.40
SCN1A P35498 2/20 0.40
SCN5A Q14524 2/20 0.40
SCN9A Q15858 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
NFKB1 P19838 2/20 0.40
ACHE P22303 1/20 0.40
CYP2C9 P11712 1/20 0.40
KCNK3 O14649 1/20 0.40
CACNA1F O60840 1/20 0.40
KCNK2 O95069 1/20 0.40
GBA1 P04062 1/20 0.40
MAOA P21397 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850798 0.76 CYP1A2 (0.31) CYP1A2CYP2A6TSHR
SCHEMBL437049 0.73 HSP90AA1 (0.50) CYP1A2CYP2A6SCN4ATSHRLMNA
SCHEMBL4854380 0.72 RAPGEF4 (0.38) CYP1A2CYP2A6TSHRLMNAACHE
SCHEMBL4849506 0.72 MAPT (0.48) CYP1A2CYP2A6LMNACYP3A4CYP2D6
SCHEMBL145464 0.71 ALDH1A1 (0.48) CYP1A2CYP2A6SCN4ATSHRLMNA
Phosphine SCHEMBL21753753 0.71 HSP90AA1 (0.48) CYP1A2CYP2A6SCN4ATSHRLMNA
SCHEMBL4852643 0.70 TSHR (0.46) CYP1A2SCN4ATSHRCYP2D6ACHE
SCHEMBL4821766 0.69 CYP1A2 (0.43) CYP1A2CYP2A6SCN4ATSHRLMNA
SCHEMBL3288767 0.69 CYP1A2 (0.43) CYP1A2CYP2A6SCN4ATSHRLMNA
SCHEMBL1046570 0.69 CYP1A2 (0.43) CYP1A2CYP2A6SCN4ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 US disclosed
US-7186667-B2 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-06 US disclosed
US-7115539-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed
US-7008897-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20040209763-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-20040186009-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209762-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer AP1M1, PYM1, SEM1 CYP1A2 2200/4885CYP2A6 3512/4885SCN4A 837/4885
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 CYP1A2 146/4885CYP2A6 293/4885SCN4A 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.