SCHEMBL4849552

SCHEMBL4849552

COc1cccc(OC)c1N1CCNCC1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 5/20 0.66
ADRB1 P08588 4/20 0.66
HTR3E A5X5Y0 3/20 0.66
HTR3B O95264 3/20 0.66
HTR3D Q70Z44 3/20 0.66
HTR3C Q8WXA8 3/20 0.66
SIGMAR1 Q99720 2/20 0.66
DRD2 P14416 1/20 0.66
CYP2C19 P33261 1/20 0.66
DRD3 P35462 1/20 0.66
HTR6 P50406 1/20 0.66
LMNA P02545 1/20 0.64
MAPT P10636 1/20 0.64
HTR7 P34969 4/20 0.59
HTR1A P08908 3/20 0.58
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8700015 0.90 HTR3A (0.58) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL31651649 0.88 HTR3A (0.57) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL31167417 0.88 ADRB1 (0.57) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL2541843 0.88 HTR3A (0.57) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL31167421 0.88 ADRB1 (0.57) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL9523382 0.88 HTR3A (0.57) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL31652078 0.87 HTR1A (0.61) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL14355748 0.82 ALDH1A1 (0.51) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL379 0.79 HTR3A (1.00) HTR3AADRB1HTR3EHTR3BHTR3D
SCHEMBL29396943 0.79 HTR3A (1.00) HTR3AADRB1HTR3EHTR3BHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214977-A1 STAT6 INHIBITORS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-07-03 US disclosed
EP-3363645-B1 PRETREATMENT OF UV CURED INK UNDER-LAYERS XEROX CORP (US) 2019-10-23 EP disclosed
CN-104177923-B Ultraviolet curing water-based ink, print cartridge, recording device and recording method 富士施乐株式会社 2019-01-29 CN disclosed
EP-3375621-A2 TWO COMPONENT INK JETTABLE PRIMER AND INCORPORATION OF ADHESION PROMOTER TO THE INK FOR PRINTING ONTO 3D OBJECTS Xerox Corporation (US) 2018-09-19 EP disclosed
EP-3363645-A1 PRETREATMENT OF UV CURED INK UNDER-LAYERS Xerox Corporation (US) 2018-08-22 EP disclosed
US-10005294-B1 Two component ink jettable primer and incorporation of adhesion promoter to the ink for printing onto 3D objects XEROX CORPORATION (US) 2018-06-26 US disclosed
US-9969185-B1 Pretreatment of UV cured ink under-layers XEROX CORPORATION (US) 2018-05-15 US disclosed
US-9498976-B2 Ultraviolet-curable aqueous ink, ink cartridge, recording apparatus and recording method FUJI XEROX CO., LTD. (JP) 2016-11-22 US disclosed
US-9056999-B2 Ultraviolet-curable aqueous ink, ink cartridge, recording apparatus and recording method FUJI XEROX CO., LTD. (JP) 2015-06-16 US disclosed
CN-104231742-A ULTRAVIOLET-CURABLE AQUEOUS INK, INK CARTRIDGE, RECORDING APPARATUS AND RECORDING METHOD FUJI XEROX CO LTD 2014-12-24 CN disclosed
US-7468369-B2 Sulfonyl pyrrolidines, method for producing the same and their use as drugs SANOFI-AVENTIS (FR) 2008-12-23 US disclosed
US-20080045540-A1 SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-02-21 US disclosed
EP-1836180-A2 SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS sanofi-aventis (FR) 2007-09-26 EP disclosed
WO-2006072393-A2 SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS SANOFI-AVENTIS (DE) 2006-07-13 WO disclosed
EP-0563345-B1 NOVEL 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES MCNEILAB INC (US) 2002-07-03 EP disclosed
US-5569659-A ANTIPSYCHOTIC AGENT MCNEILAB, INC. (US) 1996-10-29 US disclosed
EP-0563345-A1 NOVEL 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES MCNEILAB, INC. (US) 1993-10-06 EP disclosed
EP-0562049-A1 NOVEL 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES MCNEILAB, INC. (US) 1993-09-29 EP disclosed
WO-1993004682-A1 NOVEL 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES MCNEILAB, INC. (US) 1993-03-18 WO disclosed
WO-1993004684-A1 NOVEL 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES MCNEILAB, INC. (US) 1993-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045540-A1 SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS SLC5A1, SLC5A2, KCNJ1 HTR3A 2464/4885ADRB1 1137/4885HTR3E 3673/4885
US-20250214977-A1 STAT6 INHIBITORS AND USES THEREOF STAT6, STAT5B, STAT5A HTR3A 4148/4885ADRB1 2760/4885HTR3E 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.