Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.65 |
| ▸ | SPR | P35270 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892369 | 0.86 | FAAH (0.74) | FAAHTRPV1MTNR1AMTNR1B | |
| SCHEMBL4856104 | 0.86 | FAAH (1.00) | FAAHTRPV1 | |
| SCHEMBL8802151 | 0.84 | TRPM8 (0.66) | FAAHTRPV1NOTUMMTNR1AMTNR1B | |
| SCHEMBL20242784 | 0.83 | NOTUM (0.78) | TRPV1NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL23925476 | 0.81 | MAPT (0.76) | TRPV1NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL8194888 | 0.81 | NOTUM (0.70) | TRPV1NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL8802739 | 0.80 | NOTUM (0.65) | TRPV1NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL14077525 | 0.80 | NOTUM (0.72) | TRPV1NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL4512654 | 0.79 | MTNR1A (1.00) | NOTUMMTNR1AMTNR1BSPR | |
| SCHEMBL9936146 | 0.79 | CDK4 (0.78) | TRPV1NOTUMMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348354-B2 | Cyclohexylurea compounds | GRUENENTHAL GMBH (DE) | 2008-03-25 | — | — | US | disclosed |
| US-20050261358-A1 | antinociceptive agent of opioid-receptor for treating pain; tert-aminecyclohexyl-urea, or -thiourea, or -amide derivatives; 1-(4-dimethylamino-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride; stereoisomers; racemic mixtures | GRUENENTHAL GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261358-A1 | antinociceptive agent of opioid-receptor for treating pain; tert-aminecyclohexyl-urea, or -thiourea, or -amide derivatives; 1-(4-dimethylamino-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride; stereoisomers; racemic mixtures | OPRL1, OPRM1, OGFRL1 | FAAH 893/4885TRPV1 69/4885NOTUM 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.