SCHEMBL4852210

SCHEMBL4852210

CC(C)(c1ccccc1)c1cc(CO)c(O)c(CO)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLF10 Q13118 1/20 0.55
ESR1 P03372 5/20 0.52
ESR2 Q92731 5/20 0.52
CYP3A4 P08684 3/20 0.52
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 2/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
CNR1 P21554 4/20 0.46
CNR2 P34972 4/20 0.46
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 2/20 0.39
HIF1A Q16665 2/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AR P10275 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8352666 0.91 KLF10 (0.50) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL18969699 0.90 KLF10 (0.49) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL10051856 0.89 KLF10 (0.59) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL26134510 0.88 ALOX15 (0.61) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL224429 0.88 ALOX15 (0.61) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL14028985 0.86 ALOX15 (0.59) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL1025007 0.85 GABRA1 (0.52) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL10051855 0.85 ESR1 (0.52) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL8733565 0.85 KLF10 (0.59) KLF10ESR1ESR2CYP3A4ALDH1A1
SCHEMBL18101031 0.84 KLF10 (0.50) KLF10ESR1ESR2CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470493-B2 Imaging member XEROX CORPORATION (US) 2008-12-30 US disclosed
US-20070099130-A1 Developer for recording materials CHEMIPRO KASEI KAISHA, LTD. (JP) 2007-05-03 US disclosed
US-20070020539-A1 Imaging member XEROX CORPORATION 2007-01-25 US disclosed
EP-1637337-A1 DEVELOPER FOR RECORDING MATERIALS Asahi Kasei Chemicals Corporation (JP) 2006-03-22 EP disclosed
EP-0369219-B1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AG (DE) 1995-01-04 EP disclosed
US-5114816-A RADIATION-SENSITIVE COMPOUNDS, RADIATION-SENSITIVE MIXTURE PREPARED THEREWITH AND COPYING MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-19 US disclosed
EP-0369219-A1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-23 EP disclosed