SCHEMBL4852543

SCHEMBL4852543

[CH2]COC(=O)COC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
HSD17B10 Q99714 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.35
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
PGR P06401 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
HTR1A P08908 1/20 0.34
CHRNB2 P17787 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22553 0.81
SCHEMBL4849094 0.78 ALDH1A1 (0.45) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5
SCHEMBL4854022 0.77
SCHEMBL1006090 0.77 ALDH1A1 (0.65) ALDH1A1HSD17B10LMNASMN1; SMN2TSHR
SCHEMBL7550561 0.77 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5
SCHEMBL6966687 0.77
SCHEMBL11208297 0.77 ALDH1A1 (0.52) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5
SCHEMBL7365892 0.76 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5
SCHEMBL118942 0.76 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5
SCHEMBL8669971 0.75 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNASMN1; SMN2CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378548-B2 Tertiary amine compounds having an ester structure and processes for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-05-27 US claimed
US-20060217570-A1 Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same SHIN-ETSU CHEMICAL CO., LTD. 2006-09-28 US claimed
US-7378548-B2 Tertiary amine compounds having an ester structure and processes for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-05-27 US disclosed
EP-1253138-B1 Novel tertiary amine compounds having an ester structure and processes for preparing same SHINETSU CHEMICAL CO (JP) 2007-06-27 EP disclosed
US-7202018-B2 Silver salt photothermographic dry imaging material KONICA CORPORATION (JP) 2007-04-10 US disclosed
US-20060217570-A1 Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same SHIN-ETSU CHEMICAL CO., LTD. 2006-09-28 US disclosed
US-7105288-B2 Mixture of organosilvr compound, sailver halide emulsion and reducing agents KONICA CORPORATION (JP) 2006-09-12 US disclosed
EP-1398663-B1 Silver salt photothermographic dry imaging material KONICA CORP (JP) 2006-08-30 EP disclosed
US-7084303-B2 Tertiary amine compounds having an ester structure and processes for preparing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-08-01 US disclosed
US-6958209-B2 Photothermographic material and image forming method KONICA CORPORATION (JP) 2005-10-25 US disclosed
US-6808872-B2 CONCERNS IN PROCESSING OF PHOTOGRAPHIC FILM WITH RESPECT TO EFFLUENT PRODUCED FROM WET-PROCESSING OF IMAGE-FORMING MATERIALS, AND RECENTLY, REDUCTION OF THE PROCESSING EFFLUENT IS STRONGLY DEMANDED IN TERMS OF ENVIRONMENTAL PROTECTION AND KONICA CORPORATION (JP) 2004-10-26 US disclosed
US-6649338-B2 Black-and-white imaging; minimal unevenness in density; enhanced sensitivity; superior image tone KONICA CORPORATION (JP) 2003-11-18 US disclosed
US-20030175630-A1 Silver salt photothermographic imaging material KONICA CORPORATION (JP) 2003-09-18 US disclosed
EP-1327909-A2 Photothermographic material and image forming method Konica Corporation (JP) 2003-07-16 EP disclosed
US-20030124473-A1 Silver salt photothermographic imaging material KONICA CORPORATION (JP) 2003-07-03 US disclosed
US-6582898-B2 Mixture of organosilver salt, silver halide emulsions, reducing agent and binder KONICA CORPORATION (JP) 2003-06-24 US disclosed
US-20020193622-A1 Novel tertiary amine compounds having an ester structure and processes for preparing same SHIN-ETSU CHEMICAL CO., LTD. 2002-12-19 US disclosed
EP-1253138-A2 Novel tertiary amine compounds having an ester structure and processes for preparing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-10-30 EP disclosed
US-20020119406-A1 Silver salt photothermographic material KONICA CORPORATION (JP) 2002-08-29 US disclosed
EP-1215530-A2 Silver salt photothermographic material KONICA CORPORATION (JP) 2002-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193622-A1 Novel tertiary amine compounds having an ester structure and processes for preparing same PHOSPHO1, NAAA, DDAH1 ALDH1A1 87/4885HSD17B10 1743/4885LMNA 932/4885
US-20060217570-A1 Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same HRH3, HRH4, HRH2 ALDH1A1 551/4885HSD17B10 1223/4885LMNA 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.