SCHEMBL4852992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8291557	0.88	ADRB1 (0.61)	HTR1ASLC6A2SLC6A4ADRB1HTR6
	Ethoxycarbonyl Group SCHEMBL27671026	0.86	HTR1A (0.46)	HTR1ASLC6A2SLC6A4ADRB1HTR6
	Hydrochloric Acid SCHEMBL7836810	0.86	HTR1A (0.59)	HTR1ASLC6A2SLC6A4ADRB1HTR6
	Hydrochloric Acid SCHEMBL4858570	0.84	ADRA2C (0.45)	HTR1ASLC6A2SLC6A4HTR6HTR3A
	SCHEMBL28291412	0.83	ADRB1 (0.59)	HTR1ASLC6A2SLC6A4ADRB1HTR6
	SCHEMBL27773198	0.81	HTR2C (0.39)	HTR1ASLC6A2SLC6A4HTR6HTR2A
	SCHEMBL4851226	0.81	HTR5A (0.45)	HTR1ASLC6A2SLC6A4ADRB1DRD2
	Hydrochloric Acid SCHEMBL4856076	0.81	HTR1A (0.45)	HTR1AHTR6DRD2DRD3LMNA
	SCHEMBL4856101	0.80	ADRB1 (0.56)	HTR1ASLC6A2SLC6A4ADRB1HTR6
	SCHEMBL4849498	0.80	ADRB1 (0.56)	HTR1ASLC6A2SLC6A4ADRB1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.