Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899512 | 0.89 | TERT (0.61) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL29549001 | 0.89 | TERT (0.61) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL4861829 | 0.88 | APP (0.42) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL2854081 | 0.88 | TERT (0.59) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL31741233 | 0.88 | TERT (0.59) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| Perchlorate SCHEMBL891055 | 0.86 | TERT (0.54) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL1259938 | 0.86 | TERT (0.58) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL10485747 | 0.75 | ALDH1A1 (0.54) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL15423130 | 0.73 | TERT (0.74) | TERTKMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL5114156 | 0.73 | TERT (0.43) | TERTKMT2AL3MBTL1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326258-B2 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2005-12-22 | — | — | US | claimed |
| EP-1607393-A1 | Compositions comprising hydroalkylated direct dyestuffs, process for implementing and use | L'OREAL (FR) | 2005-12-21 | — | — | EP | claimed |
| US-7326258-B2 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | KRT18, DSG1, CUTA | TERT 509/4885KMT2A 1522/4885L3MBTL1 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.