Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856935 | 0.88 | TERT (0.50) | TERTSLC29A1MAPTKMT2AMEN1 | |
| SCHEMBL3899512 | 0.76 | TERT (0.61) | TERTMAPTKMT2AMEN1LMNA | |
| SCHEMBL29549001 | 0.76 | TERT (0.61) | TERTMAPTKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL31741233 | 0.74 | TERT (0.59) | TERTMAPTKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL2854081 | 0.74 | TERT (0.59) | TERTMAPTKMT2AMEN1LMNA | |
| Perchlorate SCHEMBL891055 | 0.74 | TERT (0.54) | TERTMAPTKMT2AMEN1LMNA | |
| SCHEMBL13107609 | 0.73 | APAF1 (0.43) | APPTERTPSMB5APAF1EGFR | |
| Hydrochloric Acid SCHEMBL1259938 | 0.73 | TERT (0.58) | TERTMAPTKMT2AMEN1LMNA | |
| SCHEMBL6273733 | 0.70 | KMT2A (0.38) | TERTMAPTKMT2AMEN1LMNA | |
| SCHEMBL6271438 | 0.70 | NPC1 (0.43) | APPTERTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326258-B2 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2005-12-22 | — | — | US | claimed |
| EP-1607393-A1 | Compositions comprising hydroalkylated direct dyestuffs, process for implementing and use | L'OREAL (FR) | 2005-12-21 | — | — | EP | claimed |
| US-7326258-B2 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | L'OREAL S.A. (FR) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050278872-A1 | Compositions comprising hydroxyalkyl direct dyes, implementation processes and uses thereof | KRT18, DSG1, CUTA | APP 1324/4885TERT 509/4885PSMB5 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.