SCHEMBL4858283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13987709	0.89	HTR1A (0.47)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL4856265	0.88	HTR1A (0.42)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL4855574	0.88	MAOA (0.51)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL4851846	0.87	DRD3 (0.44)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL6035065	0.82	HDAC3 (0.49)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL4861331	0.82	CASP3 (0.54)	ALDH1A1GAA
	SCHEMBL6035044	0.81	HDAC3 (0.51)	HTR1AHTR2AHTR7DRD3DRD4
	Hydrochloric Acid SCHEMBL4861062	0.81	HDAC3 (0.48)	HTR1AHTR2AHTR7DRD3DRD4
	SCHEMBL4855307	0.81	CASP3 (0.54)	ALDH1A1GAA
	Hydrochloric Acid SCHEMBL4910371	0.81	HDAC3 (0.50)	HTR1AHTR2AHTR7DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.