Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858283 | 0.89 | HTR1A (0.46) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL4856265 | 0.86 | HTR1A (0.42) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL6034218 | 0.86 | ACHE (0.39) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL4854986 | 0.85 | ACHE (0.39) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL6035065 | 0.84 | HDAC3 (0.49) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL4861062 | 0.83 | HDAC3 (0.48) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL6035044 | 0.83 | HDAC3 (0.51) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL6034293 | 0.83 | CASP3 (0.53) | ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4910371 | 0.82 | HDAC3 (0.50) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL6035070 | 0.82 | ALDH1A1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |