Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860689 | 1.00 | INSR (0.66) | INSRMAPTPOLBKMT2AMEN1 | |
| Sulfuric Acid SCHEMBL4862781 | 0.95 | INSR (0.60) | INSRMAPTPOLBKMT2AMEN1 | |
| Sulfuric Acid SCHEMBL4862784 | 0.95 | INSR (0.60) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL4864650 | 0.93 | INSR (0.58) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL21140925 | 0.90 | INSR (0.77) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL5772477 | 0.88 | INSR (0.69) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL5772480 | 0.88 | INSR (0.69) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL6033699 | 0.86 | INSR (0.65) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL6033696 | 0.86 | INSR (0.65) | INSRMAPTPOLBKMT2AMEN1 | |
| SCHEMBL14268550 | 0.84 | INSR (0.56) | INSRMAPTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |
| EP-1618865-A1 | Use of polycationic compounds for dyeing keratin fibres | L'OREAL (FR) | 2006-01-25 | — | — | EP | claimed |
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20060037151-A1 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL | 2006-02-23 | — | — | US | disclosed |
| EP-1618865-A1 | Use of polycationic compounds for dyeing keratin fibres | L'OREAL (FR) | 2006-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060037151-A1 | Use of polycationic compounds in the dyeing of keratinous fibres | KRT18, KRTCAP2, DSG1 | INSR 4778/4885MAPT 137/4885POLB 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.