SCHEMBL5772477

SCHEMBL5772477

CCN(CCO)c1ccc(/N=N/c2sc3cc(OC)ccc3[n+]2C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INSR P06213 6/20 0.69
MAPT P10636 11/20 0.43
KMT2A Q03164 5/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
PSMD14 O00487 1/20 0.43
MITF O75030 1/20 0.43
MEN1 O00255 4/20 0.39
APP P05067 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GSK3B P49841 1/20 0.37
POLB P06746 4/20 0.37
APOBEC3A P31941 1/20 0.36
TDP1 Q9NUW8 3/20 0.36
TP53 P04637 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5772480 1.00 INSR (0.69) INSRMAPTKMT2ANPC1RAB9A
Basic Blue 41 SCHEMBL94760 0.93 INSR (0.60) INSRMAPTKMT2ANPC1RAB9A
Basic Blue 41 SCHEMBL29366785 0.93 INSR (0.60) INSRMAPTKMT2ANPC1RAB9A
Basic Blue 41 SCHEMBL110712 0.93 INSR (0.60) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL21140925 0.92 INSR (0.77) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL24591189 0.91 INSR (0.56) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL24591187 0.89 INSR (0.53) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL4860682 0.88 INSR (0.66) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL4860689 0.88 INSR (0.66) INSRMAPTKMT2ANPC1RAB9A
SCHEMBL24591190 0.88 INSR (0.74) INSRMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377787-B2 Basic dye mixtures for aramid fibres DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2022-07-05 US disclosed
WO-2020008074-A1 HAIR COLORING COMPOSITION AND METHODS FOR ITS APPLICATION AND REMOVAL HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 WO disclosed
US-9670330-B2 Method and dye mixtures for marking shape memory polymers, and shape memory polymer articles with switchable readability BAM Bundesanstalt fuer Materialforschung und—Pruefung (DE) 2017-06-06 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-20150353485-A1 SECURITY ELEMENT HAVING VOLUME HOLOGRAM AND PRINTED FEATURE COVESTRO DEUTSCHLAND AG (DE) 2015-12-10 US disclosed
US-9150693-B2 Preparation of sulfonated naphthalene polyoxadiazoles polymers E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-06 US disclosed
EP-2771392-A2 METHOD AND DYE MIXTURES FOR MARKING SHAPE MEMORY POLYMERS, AND SHAPE MEMORY POLYMER ARTICLES WITH SWITCHABLE READABILITY BAM Bundesanstalt für Materialforschung und -prüfung (DE) 2014-09-03 EP disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
WO-2012152584-A1 CHROMOPHORES WITH PERFLUOROALKYL SUBSTITUENTS BASF SE (DE) 2012-11-15 WO disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 US disclosed
WO-2011084803-A2 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-07-14 WO disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed
EP-2142011-B1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2011-01-12 EP disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 US disclosed
US-20090087916-A1 Assay method for identifying drug candidate ANGESMG, INC. (JP) 2009-04-02 US disclosed
WO-2008102018-A2 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2008-08-28 WO disclosed
WO-2008102019-A2 USE OF WATER-DISPERSIBLE CAROTINOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTINOID NANOPARTICLES, AND METHOD FOR TASTE MODULATION BASF SE (DE) 2008-08-28 WO disclosed
EP-1733760-A1 Colourants for keratin fibres comprising certain cationic cellulose ether derivatives Wella Aktiengesellschaft (DE) 2006-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353485-A1 SECURITY ELEMENT HAVING VOLUME HOLOGRAM AND PRINTED FEATURE SHH, ABL1, MKI67 INSR 4325/4885MAPT 1247/4885KMT2A 1662/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 INSR 4704/4885MAPT 2715/4885KMT2A 1622/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 INSR 4704/4885MAPT 2715/4885KMT2A 1622/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 INSR 4704/4885MAPT 2715/4885KMT2A 1622/4885
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION TAS2R13, TAS2R10, TAS2R16 INSR 1766/4885MAPT 1185/4885KMT2A 4302/4885
US-20090087916-A1 Assay method for identifying drug candidate IAPP, APP, PCNP INSR 1409/4885MAPT 253/4885KMT2A 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.