Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4862781 | 1.00 | INSR (0.60) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4864650 | 0.97 | INSR (0.58) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4860682 | 0.95 | INSR (0.66) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4860689 | 0.95 | INSR (0.66) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| Basic Blue 41 SCHEMBL29366785 | 0.86 | INSR (0.60) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| Basic Blue 41 SCHEMBL94760 | 0.86 | INSR (0.60) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| Basic Blue 41 SCHEMBL110712 | 0.86 | INSR (0.60) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21140925 | 0.85 | INSR (0.77) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5772477 | 0.84 | INSR (0.69) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5772480 | 0.84 | INSR (0.69) | INSRMAPTMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | disclosed |
| US-20060037151-A1 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060037151-A1 | Use of polycationic compounds in the dyeing of keratinous fibres | KRT18, KRTCAP2, DSG1 | INSR 4778/4885MAPT 137/4885MAPK1 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.