Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4862784 | 0.97 | INSR (0.60) | INSRMAPTPOLBALDH1A1RAB9A | |
| Sulfuric Acid SCHEMBL4862781 | 0.97 | INSR (0.60) | INSRMAPTPOLBALDH1A1RAB9A | |
| SCHEMBL4860682 | 0.93 | INSR (0.66) | INSRMAPTPOLBALDH1A1RAB9A | |
| SCHEMBL4860689 | 0.93 | INSR (0.66) | INSRMAPTPOLBALDH1A1RAB9A | |
| Basic Blue 41 SCHEMBL110712 | 0.90 | INSR (0.60) | INSRMAPTPOLBALDH1A1RAB9A | |
| Basic Blue 41 SCHEMBL29366785 | 0.90 | INSR (0.60) | INSRMAPTPOLBALDH1A1RAB9A | |
| Basic Blue 41 SCHEMBL94760 | 0.90 | INSR (0.60) | INSRMAPTPOLBALDH1A1RAB9A | |
| Methacrylic Acid SCHEMBL600099 | 0.84 | INSR (0.53) | INSRMAPTPOLBALDH1A1RAB9A | |
| SCHEMBL23064864 | 0.84 | INSR (0.61) | INSRMAPTPOLBALDH1A1RAB9A | |
| SCHEMBL21140925 | 0.84 | INSR (0.77) | INSRMAPTPOLBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326259-B2 | Use of polycationic compounds in the dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2008-02-05 | — | — | US | claimed |