Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206004 | 0.92 | FFAR4 (0.41) | TDP1LMNAFFAR4HSD11B1MAPK1 | |
| SCHEMBL3201709 | 0.88 | FFAR1 (0.40) | LMNAFFAR4HSD11B1CYP3A4CYP2D6 | |
| SCHEMBL3127290 | 0.88 | CA12 (0.40) | TDP1LMNACA12CA9CA1 | |
| SCHEMBL12039381 | 0.85 | LMNA (0.37) | TDP1LMNAHSD11B1MAPK1HTT | |
| Trifluoromethanesulfonic Acid SCHEMBL4857072 | 0.85 | GPR3 (0.47) | FFAR4HSD11B1CYP3A4CYP2D6MAPK1 | |
| SCHEMBL424810 | 0.85 | CYP2A6 (0.37) | TDP1LMNAHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL3191490 | 0.85 | HSD11B1 (0.34) | RAPGEF4TDP1LMNAFFAR4HSD11B1 | |
| SCHEMBL5408836 | 0.84 | TSHR (0.37) | CA2CYP3A4HTTSMN1; SMN2GAA | |
| SCHEMBL5408447 | 0.84 | FFAR1 (0.39) | LMNAFFAR4CA1CA2CYP3A4 | |
| SCHEMBL3193928 | 0.84 | HTT (0.33) | RAPGEF4TDP1LMNAHSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072720-B2 | Aqueous ink, ink cartridge and ink jet recording method | CANON KABUSHIKI KAISHA (JP) | 2021-07-27 | — | — | US | disclosed |
| US-20200071554-A1 | AQUEOUS INK, INK CARTRIDGE AND INK JET RECORDING METHOD | CANON KABUSHIKI KAISHA (JP) | 2020-03-05 | — | — | US | disclosed |
| US-7323284-B2 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-6723483-B1 | Sulfonium salt compounds | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1113005-B1 | Sulfonium salt compounds | WAKO PURE CHEM IND LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-20030022095-A1 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2003-01-30 | — | — | US | disclosed |
| EP-1238969-A2 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-1113005-A1 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |