Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | BCHE | P06276 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450091 | 0.84 | RAB9A (1.00) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL23360762 | 0.81 | RAB9A (0.47) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| Phenyl Dimethylcarbamate SCHEMBL491227 | 0.78 | RAB9A (0.78) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL4260342 | 0.77 | RAB9A (0.57) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| P-Tolyl Dimethylcarbamate SCHEMBL360147 | 0.77 | RAB9A (0.83) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL128884 | 0.76 | LMNA (0.58) | KMT2ANPSR1GAAALDH1A1PKM | |
| SCHEMBL9301148 | 0.75 | RAB9A (0.79) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL8867798 | 0.75 | RAB9A (0.59) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL15139541 | 0.75 | RAB9A (0.79) | RAB9AKMT2ANPSR1GAAALDH1A1 | |
| 4-Chlorophenyl Dimethylcarbamate SCHEMBL11300470 | 0.75 | RAB9A (0.79) | RAB9AKMT2ANPSR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| US-4032652-A | SUBSTITUTED 2H-PYRAN-2,6(3H)-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH DERIVATIVES AND METHODS OF INHIBITING THE ANTIGEN-ANTIBODY REACTION | SMITHKLINE CORPORATION (US) | 1977-06-28 | — | — | US | claimed |
| EP-2145884-B1 | INDOLEDIONE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8106086-B2 | Indoledione derivative | MSD K.K. (JP) | 2012-01-31 | — | — | US | disclosed |
| EP-2165830-B1 | Lithographic printing plate precursor and printing method using the same | FUJIFILM CORP (JP) | 2011-03-16 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20100071574-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2165830-A1 | Lithographic printing plate precursor and printing method using the same | Fujifilm Corporation (JP) | 2010-03-24 | — | — | EP | disclosed |
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | MSD K.K. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2145884-A1 | INDOLEDIONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-20020010330-A1 | Method of preparing pyrrolotriazin-4-one compound and method of preparing isothiocyanatoformic acid ester derivative that is a reactant used for preparing pyrrolotriazin-4-one compound | FUJI PHOTO FILM CO., LTD. | 2002-01-24 | — | — | US | disclosed |
| US-6329116-B1 | CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6316605-B1 | FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6228553-B1 | SHELF LIFE, STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-5925489-A | CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5232978-A | 1-(2-arylethyl)-pyrrolidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0483580-A2 | 1-(2-Arylethyl)-pyrrolidine | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-4203982-A | Arylmalonamidomethoxycephalosporins | SHIONOGI & CO., LTD. (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4032652-A | SUBSTITUTED 2H-PYRAN-2,6(3H)-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH DERIVATIVES AND METHODS OF INHIBITING THE ANTIGEN-ANTIBODY REACTION | SMITHKLINE CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056597-A1 | INDOLEDIONE DERIVATIVE | LIPE, IDO1, ADRA1A | RAB9A 1251/4885KMT2A 776/4885NPSR1 761/4885 |
| US-20020010330-A1 | Method of preparing pyrrolotriazin-4-one compound and method of preparing isothiocyanatoformic acid ester derivative that is a reactant used for preparing pyrrolotriazin-4-one compound | PPOX, QPCT, DDT | RAB9A 3952/4885KMT2A 911/4885NPSR1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.