SCHEMBL4863538

SCHEMBL4863538

CC1(C(=O)OC(=O)C2(C)CC3CCC2C3)CC2CCC1C2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4740020 0.87 ALDH1A1 (0.33) HSD11B1
SCHEMBL13952831 0.82 F10 (0.37) HSD11B1NR1H2NR1H3
SCHEMBL14314241 0.82 MEN1 (0.35) NR1H2
SCHEMBL8151460 0.81
SCHEMBL76705 0.80 HSD11B1 (0.36) HSD11B1
SCHEMBL12424266 0.80 HSD11B1 (0.33) HSD11B1
SCHEMBL5883622 0.80 HSD11B1 (0.33) HSD11B1
SCHEMBL18401259 0.80 EPHX2 (0.33) HSD11B1
SCHEMBL13799151 0.80 ALOX5AP (0.40) HSD11B1
SCHEMBL12968048 0.79 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7354989-B2 Thioepoxy based polymerizable composition and method for production thereof MITSUI CHEMICALS, INC. (JP) 2008-04-08 US disclosed
US-20050124783-A1 Thioepoxy based polymerizable composition and method for production thereof MITSUI CHEMICALS, INC. (JP) 2005-06-09 US disclosed
EP-0942027-B1 A polymerizable composition MITSUI CHEMICALS INC (JP) 2005-05-18 EP disclosed
EP-1484352-A1 THIOEPOXY BASED POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCTION THEREOF MITSUI CHEMICALS, INC. (JP) 2004-12-08 EP disclosed
US-6458917-B2 CURABLE; POLYSULFIDES MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
US-6365707-B1 CATALYTIC POLYEPOXIDES OR POLYTHIOEPOXIDES AND AMINO COMPOUNDS MITSUI CHEMICALS, INC. (JP) 2002-04-02 US disclosed
US-20020019511-A1 Polymerizable composition MORIJIRI HIROYUKI (JP) 2002-02-14 US disclosed
US-6300464-B2 HIGH HEAT RESISTANCE AND REFRACTIVE INDEX, LOW SPECIFIC GRAVITY; POLYMERS CONTAINING THIO(EPOXY) AND AT LEAST ONE DISULFIDE BOND MITSUI CHEMICAL, INC. (JP) 2001-10-09 US disclosed
US-20010002413-A1 Polymerizable composition MORIJIRI HIROYUKI (JP) 2001-05-31 US disclosed
US-6204311-B1 (THIO)EPOXY COMPOUND HAVING AT LEAST ONE INTRAMOLECULAR DISULFIDE BOND AND A CURING CATALYST. MITSUI CHEMICALS, INC. (JP) 2001-03-20 US disclosed
EP-0942027-A2 A polymerizable composition Mitsui Chemicals, Inc. (JP) 1999-09-15 EP disclosed