SCHEMBL76705

SCHEMBL76705

CC1(C(=O)O)CC2CCC1C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.36
MAPK1 P28482 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
THPO P40225 1/20 0.33
STAT6 P42226 1/20 0.33
HIF1A Q16665 1/20 0.33
NPC1 O15118 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MTOR P42345 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
APLNR P35414 1/20 0.32
ALOX5AP P20292 1/20 0.31
FFAR3 O14843 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11703078 0.98 HSD11B1 (0.36) HSD11B1MAPK1TP53NFKB1CYP2C19
SCHEMBL5423025 0.87 MAPK1 (0.35) HSD11B1MAPK1TP53NFKB1CYP2C19
SCHEMBL12424266 0.83 HSD11B1 (0.33) HSD11B1
SCHEMBL5883622 0.83 HSD11B1 (0.33) HSD11B1
SCHEMBL8676760 0.81 HSD11B1 (0.33) HSD11B1
SCHEMBL11703068 0.80 HSD11B1 (0.32) HSD11B1
SCHEMBL4863538 0.80 HSD11B1 (0.32) HSD11B1
SCHEMBL4740020 0.79 ALDH1A1 (0.33) HSD11B1SMN1; SMN2NPSR1
SCHEMBL8733039 0.77 HSD11B1 (0.37) HSD11B1ALOX5AP
SCHEMBL13952831 0.74 F10 (0.37) HSD11B1MAPK1CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114741819-B Small signal stability analysis method for medium-voltage direct current system based on discrete state space 华中科技大学 2024-07-16 CN claimed
CN-114741819-A Small signal stability analysis method of medium-voltage direct-current system based on discrete state space 华中科技大学 2022-07-12 CN claimed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-12572394-B2 Methods, systems and apparatus to dynamically facilitate boundaryless, high availability system management SCHNEIDER ELECTRIC SYSTEMS USA, INC. (US) 2026-03-10 US disclosed
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON 2025-04-03 US disclosed
EP-4517529-A2 METHODS, SYSTEMS AND APPARATUS TO DYNAMICALLY FACILITATE BOUNDARYLESS, HIGH AVAILABILITY SYSTEM MANAGEMENT Schneider Electric Systems USA, Inc. (US) 2025-03-05 EP disclosed
CN-114839857-B Method, system and apparatus for dynamically facilitating M: N work configuration system management 施耐德电子系统美国股份有限公司 2025-02-11 CN disclosed
CN-114741819-B Small signal stability analysis method for medium-voltage direct current system based on discrete state space 华中科技大学 2024-07-16 CN disclosed
CN-118007988-A Anti-seismic reinforcement method for reinforced concrete frame nodes with stress defects 上海应用技术大学 2024-05-10 CN disclosed
EP-4089536-B1 METHODS, SYSTEMS AND APPARATUS TO DYNAMICALLY FACILITATE BOUNDARYLESS, HIGH AVAILABILITY M:N WORKING CONFIGURATION SYSTEM MANAGEMENT SCHNEIDER ELECTRIC SYSTEMS USA INC (US) 2024-03-27 EP disclosed
US-20240093069-A1 Activatable Polymer Composition Comprising At Least Two Carboxylic Acids as Blowing Agent ZEPHYROS, INC. 2024-03-21 US disclosed
EP-1589031-A2 Production of polyketides and other natural products Biotica Technology Limited (GB) 2005-10-26 EP disclosed
EP-1299482-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING FIBRES AND METAL-CONTAINING CO-POLYMERS J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2003-04-09 EP disclosed
WO-2001094479-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING FIBRES AND METAL-CONTAINING CO-POLYMERS J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-12-13 WO disclosed
US-6090868-A ONE OR MORE ORGANIC POLYMER POWDERS WHICH ARE REDISPERSIBLE IN WATER AND ONE OR MORE ORGANOSILICON POWDERS WHICH ARE REDISPERSIBLE IN WATER ARE ADDED TO THE DRY COATING OR BINDER COMPOSITION. WACKER-CHEMIE GMBH (DE) 2000-07-18 US disclosed
US-5080892-A HYDROLYZABLE RESIN COMPOSITION AND AN ANTIFOULING COATING COMPOSITION CONTAINING THE SAME NIPPON PAINT CO., LTD. (JP) 1992-01-14 US disclosed
EP-0204456-B1 A HYDROLYZABLE RESIN COMPOSITION AND AN ANTIFOULING COATING COMPOSITION CONTAINING THE SAME Nippon Paint Co., Ltd. (JP) 1991-10-09 EP disclosed
US-4774080-A ACRYLIC RESIN, POLYESTER OR EPOXY RESIN NIPPON PAINT CO., LTD. (JP) 1988-09-27 US disclosed
EP-0204456-A1 A hydrolyzable resin composition and an antifouling coating composition containing the same Nippon Paint Co., Ltd. (JP) 1986-12-10 EP disclosed
US-4020217-A INTERLAYER OF A PLASTICIZED POLYVINYL ACETAL RESIN SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12572394-B2 Methods, systems and apparatus to dynamically facilitate boundaryless, high availability system management LBR, SAMM50, HIRA HSD11B1 638/4885MAPK1 4755/4885TP53 2210/4885
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES DHFR, CCNH, ODC1 HSD11B1 4645/4885MAPK1 4814/4885TP53 2099/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 HSD11B1 967/4885MAPK1 4004/4885TP53 2142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.