Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76705 | 0.83 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL12424266 | 0.83 | HSD11B1 (0.33) | HSD11B1ALDH1A1HTT | |
| SCHEMBL11703078 | 0.82 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL11703068 | 0.80 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL4863538 | 0.80 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL4740020 | 0.79 | ALDH1A1 (0.33) | HSD11B1ALDH1A1HTT | |
| SCHEMBL8676760 | 0.77 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL13952831 | 0.74 | F10 (0.37) | HSD11B1ALDH1A1 | |
| SCHEMBL14314241 | 0.74 | MEN1 (0.35) | ALDH1A1HTT | |
| SCHEMBL3688895 | 0.74 | HSD11B1 (0.35) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247303-A1 | 7H-dibenzo[b,g][1,5]dioxocin-5-one derivatives and use thereof | BAYER HEALTHCARE AG (DE) | 2006-11-02 | — | — | US | disclosed |
| US-7087605-B2 | 5-Ethyl-imidazotriazinones | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-08 | — | — | US | disclosed |
| EP-1560630-A2 | 7H-DIBENZO[B,G][1,5]DIOXOCIN-5-ONE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2005-08-10 | — | — | EP | disclosed |
| EP-1397363-B1 | 5-ETHYL-IMIDAZOTRIAZINONES | BAYER HEALTHCARE AG (DE) | 2005-05-11 | — | — | EP | disclosed |
| US-20040254187-A1 | 5-ethyl-imidazotriazinones | BAYER HEALTHCARE AG (DE) | 2004-12-16 | — | — | US | disclosed |
| WO-2004039453-A2 | 7H-DIBENZO[B,G][1,5]DIOXOCIN-5-ONE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2004-05-13 | — | — | WO | disclosed |
| EP-1397363-A1 | 5-ETHYL-IMIDAZOTRIAZINONES | Bayer HealthCare AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098880-A1 | 5-ETHYL-IMIDAZOTRIAZINONES | BAYER HEALTHCARE AG (DE) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254187-A1 | 5-ethyl-imidazotriazinones | EPX, TPMT, IL5 | HSD11B1 2266/4885ALDH1A1 1621/4885HTT 2109/4885 |
| US-20060247303-A1 | 7H-dibenzo[b,g][1,5]dioxocin-5-one derivatives and use thereof | CETP, APOB, MTTP | HSD11B1 177/4885ALDH1A1 3522/4885HTT 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.