Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | AQP1 | P29972 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | UTRN | P46939 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790775 | 0.83 | AQP1 (0.35) | DRD2AQP1LMNA | |
| SCHEMBL4595103 | 0.82 | NUDT1 (0.43) | NUDT1P2RX7CHRM5AQP1MAPK14 | |
| SCHEMBL4595098 | 0.81 | NUDT1 (0.42) | NUDT1P2RX7DRD2CHRM5AQP1 | |
| SCHEMBL4226069 | 0.80 | PRKAB2 (0.50) | NUDT1P2RX7CHRM5AQP1MAPK14 | |
| SCHEMBL5605796 | 0.78 | MAPK14 (0.40) | MAPK14LMNA | |
| SCHEMBL4234532 | 0.78 | AQP1 (0.57) | NUDT1P2RX7CHRM5AQP1MAPK14 | |
| SCHEMBL4234537 | 0.78 | PRKAB2 (0.41) | NUDT1P2RX7CHRM5AQP1MAPK14 | |
| SCHEMBL4965361 | 0.77 | MAPK14 (0.36) | MAPK14 | |
| SCHEMBL5140323 | 0.76 | AQP1 (0.37) | NUDT1P2RX7DRD2CHRM5AQP1 | |
| SCHEMBL4970977 | 0.76 | HTR1A (0.37) | AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874292-A2 | METHODS FOR MODULATING BLADDER FUNCTION | Wyeth (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006116169-A2 | METHODS FOR MODULATING BLADDER FUNCTION | WYETH (US) | 2006-11-02 | — | — | WO | claimed |