Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Basic Blue 41. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Basic Blue 41 SCHEMBL29366785 | 1.00 | INSR (0.60) | INSRMAPTKMT2ARAB9ANPC1 | |
| Basic Blue 41 SCHEMBL110712 | 1.00 | INSR (0.60) | INSRMAPTKMT2ARAB9ANPC1 | |
| Methacrylic Acid SCHEMBL600099 | 0.94 | INSR (0.53) | INSRMAPTKMT2ARAB9ANPC1 | |
| SCHEMBL3186033 | 0.93 | INSR (0.51) | INSRMAPTKMT2ARAB9ANPC1 | |
| SCHEMBL5772480 | 0.93 | INSR (0.69) | INSRMAPTKMT2ARAB9ANPC1 | |
| SCHEMBL5772477 | 0.93 | INSR (0.69) | INSRMAPTKMT2ARAB9ANPC1 | |
| SCHEMBL4864650 | 0.90 | INSR (0.58) | INSRMAPTKMT2ARAB9ANPC1 | |
| Sulfuric Acid SCHEMBL4862781 | 0.86 | INSR (0.60) | INSRMAPTKMT2ARAB9ANPC1 | |
| Sulfuric Acid SCHEMBL4862784 | 0.86 | INSR (0.60) | INSRMAPTKMT2ARAB9ANPC1 | |
| SCHEMBL21180865 | 0.86 | INSR (0.48) | INSRMAPTKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 989 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230262912-A1 | COVERS FOR ELECTRONIC DEVICES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2023-08-17 | — | — | US | claimed |
| US-20230189465-A1 | ELECTRONIC DEVICE COVERS WITH DYEING LAYERS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2023-06-15 | — | — | US | claimed |
| WO-2022025917-A1 | COVERS FOR ELECTRONIC DEVICES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2022-02-03 | — | — | WO | claimed |
| WO-2021230866-A1 | ELECTRONIC DEVICE COVERS WITH DYEING LAYERS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-11-18 | — | — | WO | claimed |
| EP-1928961-B1 | COLOURED COATING AND FORMULATION COMPRISING AN INDICATOR FACILITATING DETERMINING THE COATING THICKNESS | BOEING CO (US) | 2021-08-04 | — | — | EP | claimed |
| US-11054403-B2 | Cleaning composition and method for enhanced sealant adhesion | THE BOEING COMPANY (US) | 2021-07-06 | — | — | US | claimed |
| WO-2021121823-A1 | TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE | HENKEL AG & CO. KGAA (DE) | 2021-06-24 | — | — | WO | claimed |
| CN-110872789-A | Cationic dye ink composition for digital ink jet and preparation method of printed textile | 台唐工业股份有限公司 | 2020-03-10 | — | — | CN | claimed |
| US-20190331649-A1 | CLEANING COMPOSITION AND METHOD FOR ENHANCED SEALANT ADHESION | THE BOEING COMPANY (US) | 2019-10-31 | — | — | US | claimed |
| EP-3233944-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-09-04 | — | — | EP | claimed |
| US-6440177-B1 | MIXING A CATEGORY 2 BLEACHING FORMULATION ICLUDING A PERSULFATE SALT TO LIGHTEN THE COLOR OF BY MORE THAN FOUR LEVELS, A DYEING FORMULATION INCLUDING A BASIC AZO DYE THAT IS STABLE IN ABOVE FORMULATION, APPLYING THE MIXTURE TO HAIR | ARTEC SYSTEMS GROUP | 2002-08-27 | — | — | US | claimed |
| US-20020050012-A1 | One-step bleach and coloring composition for hair and method of using same | L'OREAL USA CREATIVE, INC. | 2002-05-02 | — | — | US | claimed |
| WO-2001052802-A1 | ONE-STEP BLEACH AND COLORING COMPOSITION FOR HAIR AND METHOD OF USING SAME | ARTEC SYSTEMS GROUP, INC. (US) | 2001-07-26 | — | — | WO | claimed |
| WO-2001040792-A1 | HYDROGEN PEROXIDE INDICATOR AND METHOD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-06-07 | — | — | WO | claimed |
| EP-1008600-A2 | Compositions and methods for generating red chemiluminescence | LUMIGEN, INC. (US) | 2000-06-14 | — | — | EP | claimed |
| US-6045991-A | LUCIFERIN RING SYSTEM AND AN EXOCYCLIC ENOL PHOSPHATE GROUP WHERE THE POSITION ON THE LUCIFERIN RING SYSTEM ADJACENT TO THE DOUBLE BOND IS DISUBSTITUTED; CATIONIC AROMATIC COMPOUND; REACTION WITH A PHOSPHATASE ENZYME | LUMIGEN, INC. (US) | 2000-04-04 | — | — | US | claimed |
| EP-0183717-B1 | SINGLE DYE REPLACEMENT FOR ROMANOWSKY PLURAL DYE VARIABLE COMPOSITIONS IN HUMAN BIOPSY SPECIMEN CONSTITUENT IDENTIFICATIONS | CYTOCOLOR INC. (US) | 1989-11-23 | — | — | EP | claimed |
| US-4714606-A | WATER-SOLUBLE BASIC AZO DYE, MEDICAL DIAGNOSIS | CYTOCOLOR INCORPORATED (US) | 1987-12-22 | — | — | US | claimed |
| EP-0183717-A1 | SINGLE DYE REPLACEMENT FOR ROMANOWSKY PLURAL DYE VARIABLE COMPOSITIONS IN HUMAN BIOPSY SPECIMEN CONSTITUENT IDENTIFICATIONS. | KASS LAWRENCE | 1986-06-11 | — | — | EP | claimed |
| WO-1985005446-A1 | SINGLE DYE REPLACEMENT FOR ROMANOWSKY PLURAL DYE VARIABLE COMPOSITIONS IN HUMAN BIOPSY SPECIMEN CONSTITUENT IDENTIFICATIONS | MERCK PATENT GMBH (DE) | 1985-12-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020050012-A1 | One-step bleach and coloring composition for hair and method of using same | TYR, SHH, IDO1 | INSR 3547/4885MAPT 1110/4885KMT2A 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.