Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Basic Blue 41 SCHEMBL29366785 | 0.94 | INSR (0.60) | INSRMAPTKMT2AALDH1A1POLB | |
| Basic Blue 41 SCHEMBL110712 | 0.94 | INSR (0.60) | INSRMAPTKMT2AALDH1A1POLB | |
| Basic Blue 41 SCHEMBL94760 | 0.94 | INSR (0.60) | INSRMAPTKMT2AALDH1A1POLB | |
| SCHEMBL3186033 | 0.87 | INSR (0.51) | INSRMAPTKMT2AALDH1A1POLB | |
| SCHEMBL5772477 | 0.87 | INSR (0.69) | INSRMAPTKMT2AALDH1A1POLB | |
| SCHEMBL5772480 | 0.87 | INSR (0.69) | INSRMAPTKMT2AALDH1A1POLB | |
| SCHEMBL4864650 | 0.84 | INSR (0.58) | INSRMAPTKMT2AALDH1A1POLB | |
| SCHEMBL10039843 | 0.83 | INSR (0.58) | INSRMAPTKMT2AALDH1A1POLB | |
| Sulfuric Acid SCHEMBL4862781 | 0.81 | INSR (0.60) | INSRMAPTKMT2AALDH1A1POLB | |
| Sulfuric Acid SCHEMBL4862784 | 0.81 | INSR (0.60) | INSRMAPTKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041165-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-02-16 | — | — | US | disclosed |