Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP9 | P14780 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | BMP1 | P13497 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866780 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BMAPK1MMP2MMP9 | |
| SCHEMBL4864939 | 0.93 | MMP2 (0.49) | ITGB3ITGA2BMAPK1MMP2MMP9 | |
| SCHEMBL4864934 | 0.93 | MMP2 (0.49) | ITGB3ITGA2BMAPK1MMP2MMP9 | |
| SCHEMBL5499234 | 0.91 | CTSL (0.49) | ITGB3ITGA2BMAPK1MMP2SMN1; SMN2 | |
| SCHEMBL5499235 | 0.91 | CTSL (0.49) | ITGB3ITGA2BMAPK1MMP2SMN1; SMN2 | |
| SCHEMBL5509174 | 0.88 | ADAMTS4 (0.46) | ITGB3ITGA2BMAPK1MMP2MMP9 | |
| SCHEMBL3740341 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3740339 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3740343 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BMAPK1MMP2MMP9 | |
| SCHEMBL5505502 | 0.81 | AVPR1B (0.49) | MAPK1MMP2MMP9SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | disclosed |