Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9651799 | 1.00 | — | — | |
| Fluoride SCHEMBL27745606 | 0.87 | — | — | |
| Fluoride SCHEMBL27745603 | 0.87 | — | — | |
| Fluoride SCHEMBL4338134 | 0.87 | — | — | |
| Fluoride SCHEMBL4336536 | 0.87 | — | — | |
| Fluoride SCHEMBL23456586 | 0.87 | — | — | |
| Fluoride SCHEMBL4338399 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL15224367 | 0.87 | — | — | |
| Fluoride SCHEMBL4347445 | 0.87 | — | — | |
| Fluoride SCHEMBL786791 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118835231-A | Conversion coating and preparation method thereof | 美国圣戈班性能塑料公司 | 2024-10-25 | — | — | CN | claimed |
| CN-115341281-B | Zirconium fluoride monohydrate second-order nonlinear optical crystal and preparation and application thereof | 同济大学 | 2024-02-27 | — | — | CN | claimed |
| CN-115341281-A | Second-order nonlinear optical crystal of zirconium fluoride monohydrate, preparation and application thereof | 同济大学 | 2022-11-15 | — | — | CN | claimed |
| CN-112441615-A | Preparation method of high-purity anhydrous zirconium fluoride | 严永生 | 2021-03-05 | — | — | CN | claimed |
| EP-0192514-B1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE ZIRCONIUM TETRAFLUORIDE FOR USE IN THE MANUFACTURE OF FLUORIDE GLASS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1989-05-03 | — | — | EP | claimed |
| US-20260137621-A1 | ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS | DIASOME PHARMACEUTICALS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260124139-A1 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | DIASOME PHARMACEUTICALS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20250288521-A1 | ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS | DIASOME PHARMACEUTICALS INC (US) | 2025-09-18 | — | — | US | disclosed |
| CN-118835231-A | Conversion coating and preparation method thereof | 美国圣戈班性能塑料公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118366837-A | Cleaning method and cleaning system for semiconductor equipment | 长鑫存储技术有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-115341281-B | Zirconium fluoride monohydrate second-order nonlinear optical crystal and preparation and application thereof | 同济大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-115341281-B | Zirconium fluoride monohydrate second-order nonlinear optical crystal and preparation and application thereof | 同济大学 | 2024-02-27 | — | — | CN | disclosed |
| US-20070104777-A1 | Targeted liposomal drug delivery system | TNTGAMBLE, INC. | 2007-05-10 | — | — | US | disclosed |
| US-7169410-B1 | metal targeting complex provides the targetability of the liposomal construct to the desired receptor sites of a warm-blooded host for therapy or diagnostic use | SDG, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| WO-2006127361-A2 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | SDG, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006127360-A2 | LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL | SDG, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060222698-A1 | Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal | SDG, INC. | 2006-10-05 | — | — | US | disclosed |
| US-20060222697-A1 | Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal | SDG, INC. | 2006-10-05 | — | — | US | disclosed |
| CN-1572912-A | Method of treating metal surface and metal surface treated thereby | NIPPON PAINT CO LTD (JP) | 2005-02-02 | — | — | CN | disclosed |
| US-6703518-B1 | DENTISTRY | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2004-03-09 | — | — | US | disclosed |