Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989643 | 0.95 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL11817868 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL30480483 | 0.85 | HDAC3 (0.52) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL11691288 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL8719138 | 0.85 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11815282 | 0.85 | AKR1C3 (0.47) | ALDH1A1MAPK1NPC1GAACA12 | |
| SCHEMBL2705465 | 0.84 | CES2 (0.61) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL28989846 | 0.83 | MEN1 (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28763047 | 0.82 | KDM4E (0.54) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL11270791 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989251-A | Composition comprising an additive having polycyclic aromatic groups | 伊英克公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20130281747-A1 | COBALT PHOSPHINE ALKYL COMPLEXES FOR THE ASYMMETRIC HYDROGENATION OF ALKENES | NATIONAL SCIENCE FOUNDATION | 2013-10-24 | — | — | US | disclosed |
| US-20130281747-A1 | COBALT PHOSPHINE ALKYL COMPLEXES FOR THE ASYMMETRIC HYDROGENATION OF ALKENES | NATIONAL SCIENCE FOUNDATION | 2013-10-24 | — | — | US | disclosed |
| US-7414160-B2 | Process for producing aromatic compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-08-19 | — | — | US | disclosed |
| US-20060106261-A1 | Process for producing aromatic compounds | ISHII YASUTAKA | 2006-05-18 | — | — | US | disclosed |
| US-7019179-B2 | Oxidizing aromatic compound with a heteropolyacid and/or salt or mixture containing P or Si and V, Mo or W; and eitherreducing to form a hydroxide group, coupling with O2 or alkylation or alkenylation using Pd compound catalyst | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2006-03-28 | — | — | US | disclosed |
| EP-1212309-B1 | CASPASE INHIBITOR | LG CHEM INVESTMENT LTD (KR) | 2004-08-18 | — | — | EP | disclosed |
| US-6747050-B1 | INHIBITING THE ACTIVITY OF CASPASES, PREVENTING INFLAMMATION AND APOPTOSIS | LG CHEM INVESTMENT LTD. (KR) | 2004-06-08 | — | — | US | disclosed |
| EP-1171416-B1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | LILLY CO ELI (GB) | 2004-02-18 | — | — | EP | disclosed |
| US-20030171625-A1 | Process for producing aromatic compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1212309-A1 | CASPASE INHIBITOR | LG Chem Investment, Ltd. (KR) | 2002-06-12 | — | — | EP | disclosed |
| US-6384281-B1 | USED IN TREATING NERVOUS SYSTEM DISORDERS E.G DEPRESSION, ALCOHOLISM, PAIN, HYPERTENSION, ALZHEIMER'S, MEMORY LOSS, ATTENTION-DEFICIT/OBSESSIVE COMPULSIVE/GASTRIC/CARDIOVASCULAR DISORDERS, PARKINSON'S, ANXIETY, CHRONIC FATIGUE SYNDROME, | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| EP-1171416-A1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY LIMITED (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2001021600-A1 | CASPASE INHIBITOR | LG CHEM INVESTMENT LTD. (KR) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021599-A1 | CASPASE INHIBITOR | LG CHEMICAL LTD. (KR) | 2001-03-29 | — | — | WO | disclosed |
| WO-2000061539-A1 | 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4277490-A | Insecticidal 1-(2-naphthyl)-cyclobutane carboxylate | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1981-07-07 | — | — | US | disclosed |
| EP-0003670-A1 | Preparation of alkyl 2-aryl acrylates | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1979-08-22 | — | — | EP | disclosed |
| US-3987116-A | ETHYNYLARYL COMPOUNDS AND DERIVATIVES THEREOF | WILLIAM H. RORER, INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281747-A1 | COBALT PHOSPHINE ALKYL COMPLEXES FOR THE ASYMMETRIC HYDROGENATION OF ALKENES | CPNE4, FTH1, HRH3 | ALDH1A1 2936/4885SMN1; SMN2 1252/4885MAPT 4711/4885 |
| US-20060106261-A1 | Process for producing aromatic compounds | PAH, HPD, HAO2 | ALDH1A1 1406/4885SMN1; SMN2 3753/4885MAPT 2906/4885 |
| US-20030171625-A1 | Process for producing aromatic compounds | PAH, HPD, HAO2 | ALDH1A1 1406/4885SMN1; SMN2 3753/4885MAPT 2906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.