Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL30060355 | 0.93 | — | — | |
| SCHEMBL3115471 | 0.92 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL557112 | 0.92 | — | — | |
| SCHEMBL22686936 | 0.92 | TSHR (0.31) | TSHRLMNA | |
| Hydrochloric Acid SCHEMBL10456203 | 0.92 | TSHR (0.31) | TSHRLMNA | |
| Iodide SCHEMBL1568039 | 0.92 | TSHR (0.31) | TSHRLMNA | |
| SCHEMBL9483756 | 0.92 | TSHR (0.31) | TSHRLMNA | |
| Hydrochloric Acid SCHEMBL21698 | 0.92 | TSHR (0.31) | TSHRLMNA | |
| Bromide SCHEMBL7042100 | 0.88 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL5834684 | 0.88 | ALDH1A1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616671-A | SOLVENT-FREE, HEATED REACTION OF STARCH WITH IN SITU POLYMERIZED LACTONE IN MIXTURE CONTAINING ORGANOMETALLIC POLYMERIZING AGENT | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1997-04-01 | — | — | US | claimed |
| US-5578691-A | POLYLACTONES | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1996-11-26 | — | — | US | claimed |
| US-5374744-A | Sex pheronome of Japanese beetle, cupreous chafers; oxidation, reduction, cleavage, cyclization, alkynylation, hydrolysis | JAPAN TOBACCO INC. (JP) | 1994-12-20 | — | — | US | claimed |
| CN-113072551-B | Nitrogen-containing biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114763357-B | Indolopyrimidine tricyclic compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-06-18 | — | — | CN | disclosed |
| US-20230399285-A1 | ILLUDIN ANALOGS, USES THEREOF, AND METHODS FOR SYNTHESIZING THE SAME | LANTERN PHARMA INC. (US) | 2023-12-14 | — | — | US | disclosed |
| CN-116836316-A | Method for preparing syndiotactic 1, 2-polybutadiene and regulating molecular weight by Fe-based catalyst | 青岛科技大学 | 2023-10-03 | — | — | CN | disclosed |
| US-11739043-B2 | Illudin analogs, uses thereof, and methods for synthesizing the same | LANTERN PHARMA INC. (US) | 2023-08-29 | — | — | US | disclosed |
| CN-116478329-A | Terminal-oligohydroxy liquid poly-conjugated diene rubber and preparation method and application thereof | 青岛科技大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-116355117-A | Terminal functionalized high cis-rare earth conjugated diene rubber and preparation method thereof | 青岛科技大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-111542939-A | Organic semiconductor element, organic semiconductor composition, organic semiconductor film, method for producing organic semiconductor film, and polymer for use in these | 富士胶片株式会社 | 2020-08-14 | — | — | CN | disclosed |
| CN-1473858-A | Process for producing alpha-olefine polymerized catayst and alpha-olefine polymers | 住友化学工业株式会社 | 2004-02-11 | — | — | CN | disclosed |
| WO-2003030909-A1 | 2- AND 4-AMINOPYRIMIDINES N-SUBSTTITUDED BY A BICYCLIC RING FOR USE AS KINASE INHIBITORS IN THE TREATMENT OF CANCER | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
| CN-1245773-A | Process for producing chlorine | SUMITOMO CHEMICAL CO (JP) | 2000-03-01 | — | — | CN | disclosed |
| EP-0528044-B1 | Process for producing 4-substituted gamma- lactone, and the so produced novel substances. | JAPAN TOBACCO INC (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5374744-A | Sex pheronome of Japanese beetle, cupreous chafers; oxidation, reduction, cleavage, cyclization, alkynylation, hydrolysis | JAPAN TOBACCO INC. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0528044-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED $g(g)-LACTONE, AND NOVEL SUBSTANCE | JAPAN TOBACCO INC. (JP) | 1993-02-24 | — | — | EP | disclosed |
| CN-1059529-A | [3,2-C] pyrazolyl of androgen antagonist and [3,2-d] triazolyl steroid | SCHERING AG (DE) | 1992-03-18 | — | — | CN | disclosed |
| EP-0104880-A2 | Attractant termiticidal compounds, compositions and methods of use therefor | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4304907-A | Bicyclo lactone intermediates for prostaglandin analogs | THE UPJOHN COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399285-A1 | ILLUDIN ANALOGS, USES THEREOF, AND METHODS FOR SYNTHESIZING THE SAME | SERPINC1, NUDT21, HABP2 | TSHR 1737/4885LMNA 1255/4885 |
| US-11739043-B2 | Illudin analogs, uses thereof, and methods for synthesizing the same | SERPINC1, NUDT21, HABP2 | TSHR 1737/4885LMNA 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.