Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.66 |
| ▸ | MEN1 | O00255 | 13/20 | 0.66 |
| ▸ | LMNA | P02545 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486870 | 1.00 | MAPT (0.66) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL14681380 | 0.89 | KMT2A (0.56) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL12281983 | 0.83 | KMT2A (0.54) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL12280671 | 0.83 | KMT2A (0.64) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL27864630 | 0.73 | KDM4E (0.60) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL28517448 | 0.73 | CTSV (0.52) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL15613229 | 0.73 | KMT2A (0.56) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL21925172 | 0.72 | PIM1 (0.70) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL21925171 | 0.72 | PIM1 (0.70) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL12282407 | 0.71 | AGTR1 (0.60) | MAPTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411526-A2 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | Zacharon Pharmaceuticals, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2010111711-A2 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | UGCG, MAGT1, STT3B | MAPT 4120/4885KMT2A 1738/4885MEN1 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.