Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 13/20 | 0.56 |
| ▸ | LMNA | P02545 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486870 | 0.89 | MAPT (0.66) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL486872 | 0.89 | MAPT (0.66) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL27864630 | 0.75 | KDM4E (0.60) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL12280671 | 0.74 | KMT2A (0.64) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL12281983 | 0.73 | KMT2A (0.54) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL28517448 | 0.73 | CTSV (0.52) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL21925172 | 0.72 | PIM1 (0.70) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL21925171 | 0.72 | PIM1 (0.70) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL12281174 | 0.72 | KMT2A (0.59) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL12281839 | 0.72 | AGTR1 (0.79) | KMT2AMAPTMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225610-A1 | ANTIMETASTATIC COMPOUNDS | HANSEN MARC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225610-A1 | ANTIMETASTATIC COMPOUNDS | HANSEN MARC (US) | 2013-08-29 | — | — | US | disclosed |
| US-8481553-B2 | Antimetastatic compounds | BRIGHAM YOUNG UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481553-B2 | Antimetastatic compounds | BRIGHAM YOUNG UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130035348-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-02-07 | — | — | US | disclosed |
| US-20130035348-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225610-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | KMT2A 3928/4885MAPT 4206/4885MEN1 391/4885 |
| US-20130035348-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | KMT2A 3928/4885MAPT 4206/4885MEN1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.