Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL5863228 | 0.94 | LMNA (0.35) | LMNA | |
| Butane SCHEMBL9375735 | 0.84 | LMNA (0.36) | LMNA | |
| Butane SCHEMBL4872897 | 0.82 | LMNA (0.35) | LMNA | |
| Butane SCHEMBL4879858 | 0.82 | LMNA (0.35) | LMNA | |
| Furfural SCHEMBL5622383 | 0.73 | ALDH1A1 (0.56) | LMNA | |
| Furfural SCHEMBL4869864 | 0.69 | ALDH1A1 (0.60) | LMNA | |
| SCHEMBL569625 | 0.68 | LMNA (0.43) | LMNA | |
| Butane SCHEMBL818136 | 0.67 | LMNA (0.63) | LMNA | |
| Butane SCHEMBL2557609 | 0.67 | LMNA (0.63) | LMNA | |
| SCHEMBL6712899 | 0.67 | ALDH1A1 (0.62) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188671-A1 | Simple, inexpensive synthesis of high yield and purity Suzuki coupling compounds; inhibiting rearrangement | ARCHIMICA GMBH (DE) | 2008-08-07 | — | — | US | disclosed |
| EP-0399645-B1 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1994-11-09 | — | — | EP | disclosed |
| EP-0399645-A2 | Tetrahydropyranyl derivatives, process for their preparation and pharmaceutical or veterinary compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188671-A1 | Simple, inexpensive synthesis of high yield and purity Suzuki coupling compounds; inhibiting rearrangement | CBR3, CBR1, BLVRB | LMNA 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.