Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL3645192 | 0.97 | ALDH1A1 (0.59) | ALDH1A1MAOAMAOBSMN1; SMN2SLC6A19 | |
| SCHEMBL10638856 | 0.81 | TP53 (0.41) | ALDH1A1MAOAMAOBMAPTNPSR1 | |
| SCHEMBL569625 | 0.80 | LMNA (0.43) | ALDH1A1MAOAMAOBSMN1; SMN2MAPT | |
| Benzaldehyde SCHEMBL367504 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAOAMAOBLMNAALDH1A3 | |
| SCHEMBL25518732 | 0.79 | MAOA (0.47) | ALDH1A1MAOAMAOBSMN1; SMN2MAPT | |
| SCHEMBL29391648 | 0.79 | — | — | |
| SCHEMBL4290 | 0.79 | — | — | |
| SCHEMBL17231887 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAOAMAOBSMN1; SMN2SLC6A19 | |
| SCHEMBL11216090 | 0.79 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HTTMAPTNPSR1 | |
| Ethylene SCHEMBL233909 | 0.79 | TP53 (0.39) | ALDH1A1MAOAMAOBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102140088-A | New process for synthesizing 3-bromobenzaldehyde acetal | WUHAN ZHENGQINHE ENVIRONMENTAL PROT TECHNOLOGY CO LTD | 2011-08-03 | — | — | CN | claimed |
| EP-0289669-B1 | PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES | HARDWICKE CHEMICAL COMPANY (US) | 1992-04-01 | — | — | EP | claimed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | claimed |
| US-4691033-A | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1987-09-01 | — | — | US | claimed |
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4173621-A1 | PHARMACEUTICAL COMPOSITION, ITS USE AS A DRUG AND NEW COMPOUNDS, ESPECIALLY FOR TREATING SARS-COV-2 INFECTION | Université de Bordeaux (FR) | 2023-05-03 | — | — | EP | disclosed |
| US-10875875-B2 | Propionic acid derivatives and methods of use thereof | AVIARA PHARMACEUTICALS, INC. (US) | 2020-12-29 | — | — | US | disclosed |
| CN-109251189-B | 3-piperazinyl chalcone derivatives, pharmaceutical compositions thereof and application thereof | 华东理工大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-110914242-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-3615514-A2 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | Aviara Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| CN-109251189-A | 3 piperazinyl chalcone derivatives, its pharmaceutical composition and its application | 华东理工大学 | 2019-01-22 | — | — | CN | disclosed |
| WO-2018201167-A2 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS, INC. (US) | 2018-11-01 | — | — | WO | disclosed |
| US-6080773-A | USEFUL FOR TREATMENT OF DEPRESSION, ANXIETY OR PSYCHOSIS | AKZO NOBEL, N.V. (NL) | 2000-06-27 | — | — | US | disclosed |
| EP-0289669-B1 | PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES | HARDWICKE CHEMICAL COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0289669-A1 | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4691033-A | Process for preparing 3-phenoxybenzaldehydes | HARDWICKE CHEMICAL COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875875-B2 | Propionic acid derivatives and methods of use thereof | ITGB3, ITGA1, ITGB5 | ALDH1A1 263/4885MAOA 2912/4885MAOB 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.