SCHEMBL4869092

SCHEMBL4869092

C=C(C)C(=O)OC1C2CC3CC(C2)CC1C3.CC(C)(C)OC(=O)COc1ccc(C=CC=Cc2ccc(O)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PTGS2 P35354 2/20 0.33
STAT3 P40763 1/20 0.33
ABCG2 Q9UNQ0 3/20 0.32
MAPT P10636 1/20 0.32
MAOB P27338 1/20 0.32
ESR1 P03372 3/20 0.32
HIF1A Q16665 2/20 0.32
EPAS1 Q99814 2/20 0.32
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31
HSD11B1 P28845 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842699 0.87 ELANE (0.37) KMT2ASTAT3MAPTESR1HIF1A
SCHEMBL3842870 0.86 STAT3 (0.37) MEN1KMT2ARAB9ASTAT3MAPT
SCHEMBL3843648 0.85 MEN1 (0.43) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL5436790 0.82 CYP1A2 (0.36) MEN1KMT2ANPC1RAB9ASTAT3
SCHEMBL3840650 0.81 ESR1 (0.37) MEN1KMT2ARAB9ASTAT3ABCG2
SCHEMBL5453756 0.81 MAPT (0.39) RAB9ASTAT3MAPTMAOBESR1
SCHEMBL2964490 0.80 MEN1 (0.49) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL5441675 0.80 ESR1 (0.38) MEN1KMT2ANPC1RAB9ASTAT3
SCHEMBL8050238 0.78 MEN1 (0.38) MEN1KMT2ANPC1RAB9APTGS2
SCHEMBL5454866 0.78 ESR1 (0.37) NPC1RAB9AMAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 MEN1 211/4885KMT2A 1016/4885NPC1 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.