Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609764 | 0.83 | L3MBTL1 (0.44) | L3MBTL1MAPK1MAPTALDH1A1CYP2C9 | |
| SCHEMBL919301 | 0.79 | HMGCR (0.36) | L3MBTL1PDE3BPDE3APTPN5CNR2 | |
| SCHEMBL23908217 | 0.76 | PGK1 (0.43) | PTPN5PGK1PGK2ALDH1A1KMT2A | |
| SCHEMBL4609991 | 0.76 | KDM4E (0.40) | ALDH1A1KMT2A | |
| SCHEMBL2032432 | 0.75 | PTPN5 (0.33) | PTPN5TAAR1 | |
| SCHEMBL2029811 | 0.75 | ALDH1A1 (0.42) | L3MBTL1PTPN5ALDH1A1 | |
| SCHEMBL2032329 | 0.72 | P2RX3 (0.34) | PTPN5ALDH1A1NPSR1 | |
| SCHEMBL29260864 | 0.72 | GCGR (0.42) | L3MBTL1PDE3BPDE3ATHRATHRB | |
| SCHEMBL2034116 | 0.72 | PKM (0.34) | L3MBTL1PTPN5MAPTALDH1A1CYP1A2 | |
| SCHEMBL3815603 | 0.71 | PGK1 (0.47) | PGK1PGK2THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |