Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219284 | 0.89 | DPP4 (0.41) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL4219290 | 0.89 | DPP4 (0.41) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL12436971 | 0.79 | ALDH1A1 (0.38) | ALDH1A1NPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL295163 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL4215582 | 0.77 | DPP4 (0.41) | ALDH1A1NPC1DPP4DPP7 | |
| SCHEMBL4211174 | 0.77 | DPP4 (0.41) | ALDH1A1NPC1DPP4DPP7 | |
| SCHEMBL4211177 | 0.77 | DPP4 (0.41) | ALDH1A1NPC1DPP4DPP7 | |
| SCHEMBL2696686 | 0.77 | ALDH1A1 (0.48) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL4164572 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPC1CHRM2CHRM4CHRM1 | |
| SCHEMBL21159869 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPC1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051388-A1 | Novel Compounds That Inhibit Factor Xa Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051388-A1 | Novel Compounds That Inhibit Factor Xa Activity | SERPINC1, TFPI, F11 | ALDH1A1 2230/4885NPC1 1771/4885CHRM2 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.