Butilfenin

Butilfenin

SCHEMBL487062

CCCCc1ccc(NC(=O)CN(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.62
HPGD P15428 3/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ALDH1A1 P00352 2/20 0.58
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
TRPV1 Q8NER1 1/20 0.52
HSD17B10 Q99714 1/20 0.51
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
S1PR1 P21453 1/20 0.50
GAA P10253 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4275036 0.89 S1PR1 (0.55) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL4265384 0.88 CA1 (0.55) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL7768642 0.88 CA1 (0.55) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL8772754 0.88 CA1 (0.55) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL1197762 0.88 CA1 (0.55) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL7511976 0.85 ICMT (0.54) POLBCA1CA2TRPV1S1PR1
SCHEMBL486896 0.84 CA1 (0.55) POLBHPGDNPC1RAB9AALDH1A1
SCHEMBL9312715 0.81 POLB (0.84) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL2619349 0.80 POLB (0.76) POLBHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL2019464 0.80 POLB (0.70) POLBHPGDNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
WO-2022018689-A1 MESH MATERIALS FOR CONTROLLED RELEASE OF ANTIVIRALS, METHOD AND USE UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) 2022-01-27 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal SDG, INC. (US) 2011-06-09 US claimed
WO-2011022396-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2011-02-24 WO claimed
US-7871641-B2 Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal SDG, INC. (US) 2011-01-18 US claimed
US-7858116-B2 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. (US) 2010-12-28 US claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. 2006-10-05 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1261791-A Targeted liposomal constructs for diagnostic and therapeutic uses SDG INC (US) 2000-08-02 CN claimed
EP-0999855-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, Inc. (US) 2000-05-17 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 POLB 4282/4885HPGD 1531/4885NPC1 228/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 POLB 4659/4885HPGD 2154/4885NPC1 23/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG POLB 3957/4885HPGD 1849/4885NPC1 234/4885
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal INSR, IAPP, GPR119 POLB 4755/4885HPGD 3818/4885NPC1 75/4885
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal INSR, INSRR, IAPP POLB 4685/4885HPGD 2177/4885NPC1 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.