SCHEMBL4871064

SCHEMBL4871064

C=CCC(=C)C(N)(CC=C)OC(=O)C(=C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097542 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11089429 0.75
SCHEMBL3195147 0.75 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL16553409 0.73 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL2143318 0.73 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL3675285 0.72 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL5523682 0.71 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL27820986 0.71 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL11224859 0.71 TSHR (0.33) ALDH1A1TSHR
SCHEMBL28357452 0.69 ALDH1A1 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391292-B1 COMPOSITIONS FOR FORM RETENTION OF AND/OR FIXING HAIRSTYLE WHICH PROVIDE HAIR WITH GOOD COSMETIC PROPERTIES, IN PARTICULAR GOOD DISENTANGLING, SOFTNESS AND PLEASANT APPEARANCE, IN ADDITION TO FIXING WHICH LASTS L'ORéAL S.A. (FR) 2002-05-21 US claimed
EP-3810287-A1 HAIR DYEING COMPOSITION COMPRISING AN OXIDATION DYE, A SCLEROGLUCAN GUM AND A CATIONIC POLYMER L'OREAL (FR) 2021-04-28 EP disclosed
WO-2019243511-A1 HAIR DYEING COMPOSITION COMPRISING AN OXIDATION DYE, A SCLEROGLUCAN GUM AND A CATIONIC POLYMER L'OREAL (FR) 2019-12-26 WO disclosed
EP-1579845-B1 Cosmetic composition comprising a polyglycerolated silicone elastomer L'ORÉAL (FR) 2017-04-19 EP disclosed
US-7378103-B2 Cosmetic composition comprising a polyglycerolated silicone elastomer L'OREAL (FR) 2008-05-27 US disclosed
US-20070148102-A1 Hair treament method using dry foam as mechanical support for hair PROCTER & GAMBLE COMPANY, THE 2007-06-28 US disclosed
US-20050220728-A1 Cosmetic composition comprising a polyglycerolated silicone elastomer KANJI MOHAMED 2005-10-06 US disclosed
EP-1579845-A2 Cosmetic composition comprising a polyglycerolated silicone elastomer L'OREAL (FR) 2005-09-28 EP disclosed
EP-0493320-B1 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA GEIGY AG (CH) 1996-07-31 EP disclosed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP disclosed
US-5334681-A High oxygen permeability; resiliency, flexibility; wettability; biocompatibility CIBA-GEIGY CORPORATION (US) 1994-08-02 US disclosed
US-5238554-A METHOD OF MAKING PATTERNS CIBA-GEIGY CORPORATION (US) 1993-08-24 US disclosed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050220728-A1 Cosmetic composition comprising a polyglycerolated silicone elastomer PLOD3, SGMS2, SGMS1 ALDH1A1 1731/4885TSHR 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.