Diphenylsulfane

Diphenylsulfane

SCHEMBL4871234

CC(C)(C)c1ccc(OS(=O)(=O)c2ccc(F)cc2F)cc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
ENPP1 P22413 3/20 0.38
HSD11B1 P28845 1/20 0.37
HSD17B3 P37058 1/20 0.37
MAPT P10636 2/20 0.37
RECQL P46063 1/20 0.37
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL2895786 0.79 MAPT (0.52) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL4423381 0.78 CA1 (0.42) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL2191112 0.78 CA1 (0.50) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL3981835 0.77 PIK3C3 (0.37) ALDH1A1MAPTGAAPIK3C3KDM4E
Diphenylsulfane SCHEMBL4864595 0.77 MEN1 (0.50) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL2191898 0.75 ALDH1A1 (0.51) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL2898485 0.74 ENPP1 (0.41) ALDH1A1CA1CA2CA9MEN1
SCHEMBL3195800 0.74 HSD11B1 (0.42) ALDH1A1MEN1KMT2ARAB9ANPC1
Diphenylsulfane SCHEMBL2897548 0.72 CA1 (0.43) ALDH1A1CA1CA2CA9MEN1
Diphenylsulfane SCHEMBL4425601 0.70 STS (0.44) ALDH1A1CA1CA2CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314701-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2008-01-01 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-6506537-B2 Photopolymerization JSR CORPORATION (JP) 2003-01-14 US disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed
US-20020012872-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-31 US disclosed
EP-1164433-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed