Diphenylsulfane

Diphenylsulfane

SCHEMBL3981835

Cc1cc(C)c(OS(=O)(=O)c2ccc(F)cc2F)c(C)c1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 1/20 0.37
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 3/20 0.35
NR3C1 P04150 2/20 0.35
PGR P06401 2/20 0.35
NR3C2 P08235 2/20 0.35
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP13 P45452 1/20 0.35
ADAM17 P78536 1/20 0.35
KDM4E B2RXH2 2/20 0.34
F2 P00734 1/20 0.34
MAPT P10636 1/20 0.34
GAA P10253 1/20 0.34
KAT6A Q92794 1/20 0.33
FFAR4 Q5NUL3 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
PTGS2 P35354 1/20 0.32
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL4871234 0.77 ALDH1A1 (0.44) PIK3C3ALDH1A1KDM4EMAPTGAA
Diphenylsulfane SCHEMBL4653393 0.75 NR3C1 (0.42) TSHRMAPK1ALDH1A1NR3C1PGR
Diphenylsulfane SCHEMBL3983020 0.73 MMP1 (0.39) TSHRMAPK1ALDH1A1NR3C1PGR
SCHEMBL548240 0.72 FFAR4 (0.38) TSHRMAPK1ALDH1A1NR3C1PGR
Diphenylsulfane SCHEMBL5002114 0.70 NR3C1 (0.39) TSHRALDH1A1NR3C1PGRNR3C2
SCHEMBL3200978 0.69 ALDH1A1 (0.42) TSHRMAPK1ALDH1A1KDM4EF2
SCHEMBL28115946 0.69 FFAR4 (0.51) ALDH1A1MAPTFFAR4SMN1; SMN2HTT
SCHEMBL3204764 0.68 HTR2A (0.36) TSHRMAPK1ALDH1A1KDM4EGAA
SCHEMBL2954165 0.67 HTR2A (0.39) TSHRMAPK1ALDH1A1KDM4EF2
SCHEMBL26163294 0.66 TSHR (0.46) TSHRMAPK1ALDH1A1PTGS2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8771923-B2 Radiation-sensitive composition JSR CORPORATION (JP) 2014-07-08 US disclosed
US-20130108962-A1 RADIATION-SENSITIVE COMPOSITION JSR CORPORATION (JP) 2013-05-02 US disclosed
US-8361691-B2 Radiation-sensitive composition and process for producing low-molecular compound for use therein JSR CORPORATION (JP) 2013-01-29 US disclosed
US-20090280433-A1 RADIATION-SENSITIVE COMPOSITION AND PROCESS FOR PRODUCING LOW-MOLECULAR COMPOUND FOR USE THEREIN JSR CORPORATION (JP) 2009-11-12 US disclosed
EP-2060949-A1 RADIATION-SENSITIVE COMPOSITION AND PROCESS FOR PRODUCING LOW-MOLECULAR COMPOUND FOR USE THEREIN JSR Corporation (JP) 2009-05-20 EP disclosed
US-20060188812-A1 Phenolic hydroxyl group-containing copolymer and radiation-sensitive resin composition JSR CORPORATION (JP) 2006-08-24 US disclosed
EP-1686424-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2006-08-02 EP disclosed
US-20060166138-A1 Radiation-sensitive resin composition JSR CORPORATION 2006-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090280433-A1 RADIATION-SENSITIVE COMPOSITION AND PROCESS FOR PRODUCING LOW-MOLECULAR COMPOUND FOR USE THEREIN ACP1, PLG, ALG1 PIK3C3 4880/4885TSHR 3271/4885MAPK1 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.