Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815666 | 0.91 | CHRM2 (0.56) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL17533481 | 0.86 | OPRM1 (0.70) | CHRM2CHRM3OPRM1SIGMAR1MEN1 | |
| SCHEMBL784863 | 0.82 | SIGMAR1 (0.68) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL16795159 | 0.81 | CHRM2 (0.62) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL19311894 | 0.80 | ACHE (0.62) | CHRM2CHRM3OPRM1SIGMAR1DRD2 | |
| SCHEMBL3325625 | 0.79 | CHRM2 (0.56) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL27473621 | 0.79 | SIGMAR1 (0.65) | CHRM2CHRM3OPRM1SIGMAR1MEN1 | |
| SCHEMBL1306000 | 0.78 | OPRM1 (0.61) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL9030647 | 0.78 | SIGMAR1 (0.67) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 | |
| SCHEMBL2845483 | 0.77 | KCNH2 (0.65) | CHRM2CHRM3OPRM1SIGMAR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963303-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066201-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |